Gene description for TMEM205
Gene name transmembrane protein 205
Gene symbol TMEM205
Other names/aliases UNQ501
Species Homo sapiens
 Database cross references - TMEM205
ExoCarta ExoCarta_374882
Vesiclepedia VP_374882
Entrez Gene 374882
HGNC 29631
MIM 613771
UniProt Q6UW68  
 TMEM205 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for TMEM205
Molecular Function
    protein binding GO:0005515 IPI
Subcellular Localization
    membrane GO:0016020 IEA
 Experiment description of studies that identified TMEM205 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TMEM205
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NRG1 3084
Affinity Capture-MS Homo sapiens
2 TOMM40 10452
Co-fractionation Homo sapiens
3 TMEM52B 120939
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 LMAN2 10960
Affinity Capture-MS Homo sapiens
5 NAT8B  
Affinity Capture-MS Homo sapiens
6 VAMP4 8674
Two-hybrid Homo sapiens
7 TXN2 25828
Co-fractionation Homo sapiens
8 SLC18A1  
Affinity Capture-MS Homo sapiens
9 AK2 204
Co-fractionation Homo sapiens
10 SLC25A3 5250
Co-fractionation Homo sapiens
11 ECSCR  
Affinity Capture-MS Homo sapiens
12 PKM 5315
Co-fractionation Homo sapiens
13 RAMP3  
Affinity Capture-MS Homo sapiens
14 TPM2 7169
Affinity Capture-MS Homo sapiens
15 HMOX2 3163
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 IL9R  
Affinity Capture-MS Homo sapiens
17 CD1B 910
Affinity Capture-MS Homo sapiens
18 PRDX5 25824
Co-fractionation Homo sapiens
19 TSPAN15 23555
Affinity Capture-MS Homo sapiens
20 TP53 7157
Affinity Capture-MS Homo sapiens
21 GOSR2 9570
Two-hybrid Homo sapiens
22 PLN  
Two-hybrid Homo sapiens
23 NDUFA4 4697
Affinity Capture-MS Homo sapiens
24 TMEM11 8834
Two-hybrid Homo sapiens
25 CD27  
Affinity Capture-MS Homo sapiens
26 TREX1  
Two-hybrid Homo sapiens
27 ARL6IP6  
Two-hybrid Homo sapiens
28 SLC25A20 788
Co-fractionation Homo sapiens
29 FXYD6-FXYD2  
Two-hybrid Homo sapiens
30 PLXNC1 10154
Affinity Capture-MS Homo sapiens
31 RPA3 6119
Proximity Label-MS Homo sapiens
32 GDPD5 81544
Affinity Capture-MS Homo sapiens
33 COQ9  
Affinity Capture-MS Homo sapiens
34 GLA 2717
Affinity Capture-MS Homo sapiens
35 NDUFA3  
Two-hybrid Homo sapiens
36 TRDN 10345
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 CORO1A 11151
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 STX8 9482
Two-hybrid Homo sapiens
39 ERAP1 51752
Affinity Capture-MS Homo sapiens
40 VNN1 8876
Affinity Capture-MS Homo sapiens
41 TMEM140  
Two-hybrid Homo sapiens
42 B4GALT3 8703
Affinity Capture-MS Homo sapiens
43 VDAC3 7419
Co-fractionation Homo sapiens
44 SMAGP  
Two-hybrid Homo sapiens
45 CLEC4E  
Affinity Capture-MS Homo sapiens
46 VDAC2 7417
Co-fractionation Homo sapiens
47 RBP4 5950
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 MGST3 4259
Co-fractionation Homo sapiens
49 STX6 10228
Two-hybrid Homo sapiens
50 COMT 1312
Affinity Capture-MS Homo sapiens
51 BNIP3 664
Two-hybrid Homo sapiens
52 TSPAN10 83882
Affinity Capture-MS Homo sapiens
53 SLC51B  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TMEM205 is involved
No pathways found





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