Gene description for FAM162A
Gene name family with sequence similarity 162, member A
Gene symbol FAM162A
Other names/aliases C3orf28
E2IG5
HGTD-P
Species Homo sapiens
 Database cross references - FAM162A
ExoCarta ExoCarta_26355
Vesiclepedia VP_26355
Entrez Gene 26355
HGNC 17865
MIM 608017
UniProt Q96A26  
 FAM162A identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for FAM162A
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of apoptotic process GO:0043065 IDA
    neuron apoptotic process GO:0051402 IBA
    cellular response to hypoxia GO:0071456 IBA
    cellular response to hypoxia GO:0071456 IDA
    positive regulation of release of cytochrome c from mitochondria GO:0090200 IBA
    positive regulation of release of cytochrome c from mitochondria GO:0090200 IDA
    positive regulation of cysteine-type endopeptidase activity GO:2001056 IDA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    cytosol GO:0005829 IDA
    mitochondrial membrane GO:0031966 IEA
 Experiment description of studies that identified FAM162A in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for FAM162A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ANLN 54443
Affinity Capture-MS Homo sapiens
2 HACL1 26061
Co-fractionation Homo sapiens
3 CABP2  
Affinity Capture-MS Homo sapiens
4 SSR3 6747
Co-fractionation Homo sapiens
5 UBL4A 8266
Affinity Capture-MS Homo sapiens
6 TIMM23B  
Co-fractionation Homo sapiens
7 SLC25A12 8604
Proximity Label-MS Homo sapiens
8 AIFM1 9131
Proximity Label-MS Homo sapiens
9 SPRED2 200734
Affinity Capture-MS Homo sapiens
10 ATP1A3 478
Affinity Capture-MS Homo sapiens
11 SYT6  
Affinity Capture-MS Homo sapiens
12 LMNB1 4001
Affinity Capture-MS Homo sapiens
13 PRELID1  
Affinity Capture-MS Homo sapiens
14 BSG 682
Affinity Capture-MS Homo sapiens
15 ADRB2  
Affinity Capture-MS Homo sapiens
16 SCN4A  
Affinity Capture-MS Homo sapiens
17 HCRTR2  
Affinity Capture-MS Homo sapiens
18 COX15 1355
Proximity Label-MS Homo sapiens
19 NTNG1  
Affinity Capture-MS Homo sapiens
20 SLC25A1 6576
Co-fractionation Homo sapiens
21 CDH23 64072
Affinity Capture-MS Homo sapiens
22 SLC7A14  
Affinity Capture-MS Homo sapiens
23 NDUFA4 4697
Affinity Capture-MS Homo sapiens
24 COPE 11316
Affinity Capture-MS Homo sapiens
25 SAAL1 113174
Affinity Capture-MS Homo sapiens
26 GHITM 27069
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 GPM6B 2824
Affinity Capture-MS Homo sapiens
28 MBNL1 4154
Affinity Capture-MS Homo sapiens
29 SFXN1 94081
Proximity Label-MS Homo sapiens
30 VDAC2 7417
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
31 KIAA1429 25962
Affinity Capture-MS Homo sapiens
32 CPVL 54504
Affinity Capture-MS Homo sapiens
33 MAPK6  
Affinity Capture-MS Homo sapiens
34 IWS1  
Co-fractionation Homo sapiens
35 RPA3 6119
Proximity Label-MS Homo sapiens
36 ATP2A1 487
Affinity Capture-MS Homo sapiens
37 SLC25A51  
Proximity Label-MS Homo sapiens
38 SSH3 54961
Affinity Capture-MS Homo sapiens
39 ASPH 444
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 MRPL22  
Co-fractionation Homo sapiens
41 PCDHA12  
Affinity Capture-MS Homo sapiens
42 SERBP1 26135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 TM9SF4 9777
Co-fractionation Homo sapiens
44 CALD1 800
Affinity Capture-MS Homo sapiens
45 RPL37A 6168
Cross-Linking-MS (XL-MS) Homo sapiens
46 CTNNA3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 TSPAN31 6302
Affinity Capture-MS Homo sapiens
48 PTRF 284119
Co-fractionation Homo sapiens
49 ATP2A3 489
Affinity Capture-MS Homo sapiens
50 TMEM70  
Proximity Label-MS Homo sapiens
51 MALL  
Affinity Capture-MS Homo sapiens
52 RMDN3 55177
Co-fractionation Homo sapiens
53 SRRT 51593
Co-fractionation Homo sapiens
54 SIAE 54414
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FAM162A is involved
No pathways found





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