Gene description for NPTXR
Gene name neuronal pentraxin receptor
Gene symbol NPTXR
Other names/aliases NPR
Species Homo sapiens
 Database cross references - NPTXR
ExoCarta ExoCarta_23467
Entrez Gene 23467
HGNC 7954
MIM 609474
UniProt O95502  
 NPTXR identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for NPTXR
Molecular Function
    metal ion binding GO:0046872 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified NPTXR in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for NPTXR
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NPTX1  
Invivo Homo sapiens
Invitro Homo sapiens
2 NPTX2  
Invivo Homo sapiens
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which NPTXR is involved
No pathways found





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