Gene description for OBP2A
Gene name odorant binding protein 2A
Gene symbol OBP2A
Other names/aliases LCN13
OBP
OBP2C
OBPIIa
hOBPIIa
Species Homo sapiens
 Database cross references - OBP2A
ExoCarta ExoCarta_29991
Vesiclepedia VP_29991
Entrez Gene 29991
HGNC 23380
MIM 164320
UniProt Q9NY56  
 OBP2A identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for OBP2A
Molecular Function
    odorant binding GO:0005549 IDA
    odorant binding GO:0005549 NAS
    small molecule binding GO:0036094 IEA
Biological Process
    sensory perception of chemical stimulus GO:0007606 TAS
    sensory perception of smell GO:0007608 IEA
    glucose homeostasis GO:0042593 ISS
Subcellular Localization
    extracellular space GO:0005615 IBA
 Experiment description of studies that identified OBP2A in exosomes
1
Experiment ID 234
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for OBP2A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ERBB2IP 55914
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 COL6A2 1292
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 ADRB2  
Two-hybrid Homo sapiens
4 MOXD1 26002
Affinity Capture-MS Homo sapiens
5 OBP2B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 CLN5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 TXNDC15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 LRP2 4036
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which OBP2A is involved
No pathways found





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