Gene description for PDS5B
Gene name PDS5 cohesin associated factor B
Gene symbol PDS5B
Other names/aliases APRIN
AS3
CG008
Species Homo sapiens
 Database cross references - PDS5B
ExoCarta ExoCarta_23047
Entrez Gene 23047
HGNC 20418
MIM 605333
UniProt Q9NTI5  
 PDS5B identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for PDS5B
Molecular Function
    ATP binding GO:0005524 TAS
    protein binding GO:0005515 IPI
    DNA binding GO:0003677 IEA
Biological Process
    mitotic sister chromatid cohesion GO:0007064 IMP
    regulation of cell proliferation GO:0042127 IDA
    cell division GO:0051301 IEA
    mitotic cell cycle GO:0000278 TAS
    cell proliferation GO:0008283 TAS
    negative regulation of cell proliferation GO:0008285 IDA
Subcellular Localization
    chromosome, centromeric region GO:0000775 TAS
    cytosol GO:0005829 TAS
    chromosome GO:0005694 TAS
    nucleoplasm GO:0005654 TAS
    nucleus GO:0005634 ISS
    chromatin GO:0000785 IDA
 Experiment description of studies that identified PDS5B in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PDS5B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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