Gene description for NTPCR
Gene name nucleoside-triphosphatase, cancer-related
Gene symbol NTPCR
Other names/aliases C1orf57
HCR-NTPase
Species Homo sapiens
 Database cross references - NTPCR
ExoCarta ExoCarta_84284
Vesiclepedia VP_84284
Entrez Gene 84284
HGNC 28204
UniProt Q9BSD7  
 NTPCR identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for NTPCR
Molecular Function
    DNA clamp loader activity GO:0003689 IEA
    RNA binding GO:0003723 HDA
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 IEA
    ribonucleoside triphosphate phosphatase activity GO:0017111 IMP
    CTPase activity GO:0043273 IEA
    cohesin loader activity GO:0061775 IEA
    chromatin extrusion motor activity GO:0140584 IEA
    ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA
    ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA
    membrane scission GTPase motor activity GO:1990606 IEA
Biological Process
    chromatin remodeling GO:0006338 IEA
    chromatin looping GO:0140588 IEA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    membrane GO:0016020 HDA
 Experiment description of studies that identified NTPCR in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NTPCR
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 VCAM1 7412
Affinity Capture-MS Homo sapiens
2 RAMP3  
Affinity Capture-MS Homo sapiens
3 UBE2H 7328
Affinity Capture-MS Homo sapiens
4 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
5 MYCN  
Affinity Capture-MS Homo sapiens
6 TRMT1L 81627
Co-fractionation Homo sapiens
7 SPRTN  
Affinity Capture-MS Homo sapiens
8 AUH 549
Proximity Label-MS Homo sapiens
9 VWA8 23078
Proximity Label-MS Homo sapiens
10 IFT140 9742
Affinity Capture-MS Homo sapiens
11 WDR19 57728
Affinity Capture-MS Homo sapiens
12 FBXL6  
Affinity Capture-MS Homo sapiens
13 AMBRA1  
Affinity Capture-MS Homo sapiens
14 ATG9A 79065
Proximity Label-MS Homo sapiens
15 RUVBL2 10856
Affinity Capture-MS Homo sapiens
16 ZNF746  
Affinity Capture-MS Homo sapiens
17 RPA2 6118
Affinity Capture-MS Homo sapiens
18 TPTE  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
19 RPA1 6117
Affinity Capture-MS Homo sapiens
20 FOXO1  
Affinity Capture-MS Homo sapiens
21 FOXA1  
Affinity Capture-MS Homo sapiens
22 NUPL1 9818
Affinity Capture-MS Homo sapiens
23 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 NR3C1 2908
Proximity Label-MS Homo sapiens
25 EGFR 1956
Affinity Capture-MS Homo sapiens
26 DUSP16  
Affinity Capture-MS Homo sapiens
27 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 WDR35 57539
Affinity Capture-MS Homo sapiens
29 METTL21B  
Affinity Capture-MS Homo sapiens
30 NUP35 129401
Proximity Label-MS Homo sapiens
31 TAF1  
Affinity Capture-MS Homo sapiens
32 MEPCE 56257
Affinity Capture-MS Homo sapiens
33 RIPK4  
Affinity Capture-MS Homo sapiens
34 FN1 2335
Affinity Capture-MS Homo sapiens
35 COL1A1 1277
Affinity Capture-MS Homo sapiens
36 UFL1 23376
Affinity Capture-MS Homo sapiens
37 COL1A2 1278
Affinity Capture-MS Homo sapiens
38 MAPK6  
Affinity Capture-MS Homo sapiens
39 IGLC1 3537
Affinity Capture-MS Homo sapiens
40 RUVBL1 8607
Affinity Capture-MS Homo sapiens
41 B3GNT2 10678
Affinity Capture-MS Homo sapiens
42 MYC  
Affinity Capture-MS Homo sapiens
43 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
44 DYRK1A 1859
Affinity Capture-MS Homo sapiens
45 C16orf72 29035
Affinity Capture-MS Homo sapiens
46 GPR45  
Affinity Capture-MS Homo sapiens
47 DLST 1743
Affinity Capture-MS Homo sapiens
48 CDK20  
Affinity Capture-MS Homo sapiens
49 PTPN23 25930
Affinity Capture-MS Homo sapiens
50 PPM1D  
Affinity Capture-MS Homo sapiens
51 PML 5371
Affinity Capture-MS Homo sapiens
52 C9orf72  
Affinity Capture-MS Homo sapiens
53 DDRGK1 65992
Affinity Capture-MS Homo sapiens
54 ISLR 3671
Affinity Capture-MS Homo sapiens
55 MAD2L2 10459
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 PPEF1  
Affinity Capture-MS Homo sapiens
57 STAMBP 10617
Two-hybrid Homo sapiens
58 HECW2  
Affinity Capture-MS Homo sapiens
59 PAX3  
Affinity Capture-MS Homo sapiens
60 CEBPA  
Protein-peptide Homo sapiens
61 HUWE1 10075
Affinity Capture-MS Homo sapiens
62 ITGA4 3676
Affinity Capture-MS Homo sapiens
63 HIF1A 3091
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which NTPCR is involved
No pathways found





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