Gene description for ITPR2
Gene name inositol 1,4,5-trisphosphate receptor, type 2
Gene symbol ITPR2
Other names/aliases ANHD
CFAP48
INSP3R2
IP3R2
Species Homo sapiens
 Database cross references - ITPR2
ExoCarta ExoCarta_3709
Vesiclepedia VP_3709
Entrez Gene 3709
HGNC 6181
MIM 600144
UniProt Q14571  
 ITPR2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Endothelial cells 26027894    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells Unpublished / Not applicable
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for ITPR2
Molecular Function
    inositol 1,4,5-trisphosphate-gated calcium channel activity GO:0005220 IBA
    inositol 1,4,5-trisphosphate-gated calcium channel activity GO:0005220 IMP
    inositol 1,4,5-trisphosphate-gated calcium channel activity GO:0005220 ISS
    calcium ion binding GO:0005509 IBA
    ATP binding GO:0005524 IEA
    calcium ion transmembrane transporter activity GO:0015085 TAS
    phosphatidylinositol binding GO:0035091 IBA
    transmembrane transporter binding GO:0044325 IPI
    inositol 1,4,5 trisphosphate binding GO:0070679 IBA
    scaffold protein binding GO:0097110 IPI
Biological Process
    response to hypoxia GO:0001666 IDA
    signal transduction GO:0007165 TAS
    calcium-mediated signaling GO:0019722 IEA
    release of sequestered calcium ion into cytosol GO:0051209 IBA
    release of sequestered calcium ion into cytosol GO:0051209 ISS
    cellular response to cAMP GO:0071320 IEA
    cellular response to ethanol GO:0071361 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 TAS
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    cell cortex GO:0005938 IEA
    membrane GO:0016020 HDA
    sarcoplasmic reticulum GO:0016529 IBA
    transport vesicle membrane GO:0030658 IEA
    secretory granule membrane GO:0030667 IBA
    platelet dense tubular network membrane GO:0031095 TAS
    sarcoplasmic reticulum membrane GO:0033017 IMP
    receptor complex GO:0043235 IDA
 Experiment description of studies that identified ITPR2 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
6
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
10
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ITPR2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TPRA1  
Affinity Capture-MS Homo sapiens
2 GJD3  
Proximity Label-MS Homo sapiens
3 C5AR1  
Affinity Capture-MS Homo sapiens
4 CABP2  
Affinity Capture-MS Homo sapiens
5 METTL7A 25840
Proximity Label-MS Homo sapiens
6 LAMP3  
Proximity Label-MS Homo sapiens
7 GJA1 2697
Proximity Label-MS Homo sapiens
8 BTF3 689
Affinity Capture-MS Homo sapiens
9 CTDNEP1 23399
Proximity Label-MS Homo sapiens
10 KIF20A 10112
Affinity Capture-MS Homo sapiens
11 HSD17B11 51170
Proximity Label-MS Homo sapiens
12 DNAJC25 548645
Proximity Label-MS Homo sapiens
13 PTPN1 5770
Proximity Label-MS Homo sapiens
14 SOX2  
Affinity Capture-MS Homo sapiens
15 CAPZB 832
Affinity Capture-MS Homo sapiens
16 PPL 5493
Affinity Capture-MS Homo sapiens
17 B3GAT1  
Proximity Label-MS Homo sapiens
18 KIF23 9493
Affinity Capture-MS Homo sapiens
19 CA8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 BBOX1 8424
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 PRC1 9055
Affinity Capture-MS Homo sapiens
22 CALD1 800
Affinity Capture-MS Homo sapiens
23 CALM3 808
Affinity Capture-MS Homo sapiens
24 ERGIC1 57222
Proximity Label-MS Homo sapiens
25 SSR1 6745
Proximity Label-MS Homo sapiens
26 MAD2L2 10459
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 C3orf52  
Affinity Capture-MS Homo sapiens
28 DNAJC16  
Proximity Label-MS Homo sapiens
29 TESPA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 SLC25A46 91137
Proximity Label-MS Homo sapiens
31 ATG16L1 55054
Affinity Capture-MS Homo sapiens
32 MRPS7 51081
Cross-Linking-MS (XL-MS) Homo sapiens
33 PSMC3 5702
Affinity Capture-MS Homo sapiens
34 GPR17 2840
Affinity Capture-MS Homo sapiens
35 KIF14 9928
Affinity Capture-MS Homo sapiens
36 LMAN1 3998
Proximity Label-MS Homo sapiens
37 NUP155 9631
Proximity Label-MS Homo sapiens
38 KIAA1715 80856
Proximity Label-MS Homo sapiens
39 PXMP2  
Proximity Label-MS Homo sapiens
40 FAM19A4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 EMD 2010
Proximity Label-MS Homo sapiens
42 TRPC4  
Two-hybrid Homo sapiens
43 MYH9 4627
Affinity Capture-MS Homo sapiens
44 RASEF  
Affinity Capture-MS Homo sapiens
45 IPPK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 CCDC101  
Affinity Capture-MS Homo sapiens
47 PML 5371
Affinity Capture-MS Homo sapiens
48 L3MBTL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 ELOVL5 60481
Proximity Label-MS Homo sapiens
50 SEC61B 10952
Proximity Label-MS Homo sapiens
51 REEP5 7905
Proximity Label-MS Homo sapiens
52 ANLN 54443
Affinity Capture-MS Homo sapiens
53 Sumo3  
Affinity Capture-MS Mus musculus
54 HSD3B7 80270
Proximity Label-MS Homo sapiens
55 RPN2 6185
Proximity Label-MS Homo sapiens
56 EIF4G1 1981
Cross-Linking-MS (XL-MS) Homo sapiens
57 ECT2 1894
Affinity Capture-MS Homo sapiens
58 RPL35 11224
Cross-Linking-MS (XL-MS) Homo sapiens
59 BCAP31 10134
Proximity Label-MS Homo sapiens
60 RAB29 8934
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 FKBP8 23770
Proximity Label-MS Homo sapiens
62 LPAR1 1902
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 NXF1 10482
Affinity Capture-RNA Homo sapiens
64 PRKACA 5566
Proximity Label-MS Homo sapiens
65 ATP2A1 487
Proximity Label-MS Homo sapiens
66 RAB9A 9367
Proximity Label-MS Homo sapiens
67 RPN1 6184
Proximity Label-MS Homo sapiens
68 CYP2C9  
Proximity Label-MS Homo sapiens
69 HAX1  
Proximity Label-MS Homo sapiens
70 CCDC8  
Affinity Capture-MS Homo sapiens
71 P2RY12 64805
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 RPL19 6143
Cross-Linking-MS (XL-MS) Homo sapiens
73 ZRANB1 54764
Affinity Capture-MS Homo sapiens
74 Lima1  
Affinity Capture-MS Mus musculus
75 SIRT6  
Affinity Capture-MS Homo sapiens
76 Myo1c 17913
Affinity Capture-MS Mus musculus
77 CAPZA2 830
Affinity Capture-MS Homo sapiens
78 ITPR3 3710
Affinity Capture-MS Homo sapiens
79 MAGEA9  
Affinity Capture-MS Homo sapiens
80 DDX58 23586
Affinity Capture-RNA Homo sapiens
81 NUP107 57122
Affinity Capture-MS Homo sapiens
82 SEC62 7095
Proximity Label-MS Homo sapiens
83 ZNRF4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 RAB7A 7879
Proximity Label-MS Homo sapiens
85 RAB11A 8766
Proximity Label-MS Homo sapiens
86 RPS7 6201
Cross-Linking-MS (XL-MS) Homo sapiens
87 TNNC2  
Affinity Capture-MS Homo sapiens
88 DHFRL1  
Proximity Label-MS Homo sapiens
89 DNAJC1 64215
Proximity Label-MS Homo sapiens
90 CACNG2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 CCR6  
Affinity Capture-MS Homo sapiens
92 MEN1 4221
Affinity Capture-MS Homo sapiens
93 CHRNA3 1136
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 DERL1 79139
Proximity Label-MS Homo sapiens
95 MRVI1 10335
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ITPR2 is involved
PathwayEvidenceSource
Adaptive Immune System IEA Reactome
Adaptive Immune System TAS Reactome
Anti-inflammatory response favouring Leishmania parasite infection IEA Reactome
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers IEA Reactome
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers TAS Reactome
Beta-catenin independent WNT signaling IEA Reactome
C-type lectin receptors (CLRs) IEA Reactome
Ca2+ pathway IEA Reactome
Cardiac conduction IEA Reactome
Cardiac conduction TAS Reactome
CLEC7A (Dectin-1) induces NFAT activation IEA Reactome
CLEC7A (Dectin-1) signaling IEA Reactome
DAG and IP3 signaling IEA Reactome
Disease IEA Reactome
Effects of PIP2 hydrolysis TAS Reactome
Elevation of cytosolic Ca2+ levels TAS Reactome
Fc epsilon receptor (FCERI) signaling IEA Reactome
FCERI mediated Ca+2 mobilization IEA Reactome
Fcgamma receptor (FCGR) dependent phagocytosis IEA Reactome
FCGR3A-mediated IL10 synthesis IEA Reactome
G alpha (i) signalling events IEA Reactome
G alpha (q) signalling events TAS Reactome
G-protein mediated events IEA Reactome
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion TAS Reactome
GPCR downstream signalling IEA Reactome
GPCR downstream signalling TAS Reactome
Hemostasis TAS Reactome
Immune System IEA Reactome
Immune System TAS Reactome
Infectious disease IEA Reactome
Innate Immune System IEA Reactome
Integration of energy metabolism IEA Reactome
Integration of energy metabolism TAS Reactome
Intracellular signaling by second messengers IEA Reactome
Ion homeostasis IEA Reactome
Ion homeostasis TAS Reactome
Leishmania infection IEA Reactome
Leishmania parasite growth and survival IEA Reactome
Metabolism IEA Reactome
Metabolism TAS Reactome
Muscle contraction IEA Reactome
Muscle contraction TAS Reactome
Opioid Signalling IEA Reactome
Parasitic Infection Pathways IEA Reactome
Platelet activation, signaling and aggregation TAS Reactome
Platelet calcium homeostasis TAS Reactome
Platelet homeostasis TAS Reactome
PLC beta mediated events IEA Reactome
Regulation of insulin secretion IEA Reactome
Regulation of insulin secretion TAS Reactome
Role of phospholipids in phagocytosis IEA Reactome
Signal Transduction IEA Reactome
Signal Transduction TAS Reactome
Signaling by GPCR IEA Reactome
Signaling by GPCR TAS Reactome
Signaling by Receptor Tyrosine Kinases IEA Reactome
Signaling by the B Cell Receptor (BCR) IEA Reactome
Signaling by the B Cell Receptor (BCR) TAS Reactome
Signaling by VEGF IEA Reactome
Signaling by WNT IEA Reactome
VEGFA-VEGFR2 Pathway IEA Reactome
VEGFR2 mediated cell proliferation IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here