Gene description for SLC25A17
Gene name solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
Gene symbol SLC25A17
Other names/aliases PMP34
Species Homo sapiens
 Database cross references - SLC25A17
ExoCarta ExoCarta_10478
Vesiclepedia VP_10478
Entrez Gene 10478
HGNC 10987
MIM 606795
UniProt O43808  
 SLC25A17 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for SLC25A17
Molecular Function
    adenine nucleotide transmembrane transporter activity GO:0000295 TAS
    ATP transmembrane transporter activity GO:0005347 IBA
    ATP transmembrane transporter activity GO:0005347 IGI
    protein binding GO:0005515 IPI
    ADP transmembrane transporter activity GO:0015217 IBA
    ADP transmembrane transporter activity GO:0015217 IDA
    coenzyme A transmembrane transporter activity GO:0015228 IBA
    coenzyme A transmembrane transporter activity GO:0015228 IDA
    FAD transmembrane transporter activity GO:0015230 IBA
    FAD transmembrane transporter activity GO:0015230 IDA
    antiporter activity GO:0015297 IEA
    FMN transmembrane transporter activity GO:0044610 IBA
    FMN transmembrane transporter activity GO:0044610 IDA
    protein-folding chaperone binding GO:0051087 IPI
    NAD transmembrane transporter activity GO:0051724 IBA
    NAD transmembrane transporter activity GO:0051724 IDA
    AMP transmembrane transporter activity GO:0080122 IBA
    AMP transmembrane transporter activity GO:0080122 IDA
Biological Process
    fatty acid alpha-oxidation GO:0001561 TAS
    fatty acid beta-oxidation GO:0006635 IGI
    ADP transport GO:0015866 IEA
    ATP transport GO:0015867 IGI
    fatty acid transport GO:0015908 IGI
    coenzyme A transmembrane transport GO:0035349 IEA
    FAD transmembrane transport GO:0035350 IEA
    NAD transmembrane transport GO:0035352 IEA
    AMP transport GO:0080121 IEA
    nucleotide transmembrane transport GO:1901679 IDA
Subcellular Localization
    peroxisome GO:0005777 IDA
    peroxisomal membrane GO:0005778 IBA
    peroxisomal membrane GO:0005778 IDA
    peroxisomal membrane GO:0005778 TAS
    cytosol GO:0005829 TAS
    membrane GO:0016020 HDA
 Experiment description of studies that identified SLC25A17 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SLC25A17
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 MAGEA8  
Affinity Capture-MS Homo sapiens
3 SLC39A12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 TM4SF5  
Affinity Capture-MS Homo sapiens
5 SGCA  
Affinity Capture-MS Homo sapiens
6 EIF3F 8665
Affinity Capture-MS Homo sapiens
7 ESYT2 57488
Co-fractionation Homo sapiens
8 SV2A 9900
Affinity Capture-MS Homo sapiens
9 PTH1R  
Affinity Capture-MS Homo sapiens
10 TMEM59 9528
Affinity Capture-MS Homo sapiens
11 ILF3 3609
Co-fractionation Homo sapiens
12 TSPAN15 23555
Affinity Capture-MS Homo sapiens
13 CMTM5  
Affinity Capture-MS Homo sapiens
14 UQCRB 7381
Co-fractionation Homo sapiens
15 C3AR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 LDLRAD1  
Affinity Capture-MS Homo sapiens
17 PEX19 5824
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
18 VSIG1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 SLC26A6 65010
Affinity Capture-MS Homo sapiens
20 SLC39A4 55630
Affinity Capture-MS Homo sapiens
21 IGHM 3507
Affinity Capture-MS Homo sapiens
22 ERGIC3 51614
Affinity Capture-MS Homo sapiens
23 BSCL2  
Affinity Capture-MS Homo sapiens
24 GPR12  
Affinity Capture-MS Homo sapiens
25 SAMM50 25813
Co-fractionation Homo sapiens
26 FUT8 2530
Co-fractionation Homo sapiens
27 NPY2R  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 MGARP  
Affinity Capture-MS Homo sapiens
29 KLRD1  
Affinity Capture-MS Homo sapiens
30 SLC5A6 8884
Affinity Capture-MS Homo sapiens
31 AQP3  
Affinity Capture-MS Homo sapiens
32 SLC39A9 55334
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 NXF1 10482
Affinity Capture-RNA Homo sapiens
34 HNRNPUL2 221092
Co-fractionation Homo sapiens
35 CD80 941
Affinity Capture-MS Homo sapiens
36 SLC18A2  
Affinity Capture-MS Homo sapiens
37 TSPAN8 7103
Affinity Capture-MS Homo sapiens
38 MOV10 4343
Affinity Capture-RNA Homo sapiens
39 PTGFRN 5738
Affinity Capture-MS Homo sapiens
40 PBXIP1 57326
Affinity Capture-MS Homo sapiens
41 HECW2  
Affinity Capture-MS Homo sapiens
42 ATP2A1 487
Affinity Capture-MS Homo sapiens
43 SCGB2A2  
Affinity Capture-MS Homo sapiens
44 GPR182  
Affinity Capture-MS Homo sapiens
45 ARID4B  
Affinity Capture-MS Homo sapiens
46 CUL3 8452
Affinity Capture-MS Homo sapiens
47 ARRDC3 57561
Affinity Capture-MS Homo sapiens
48 EVPL 2125
Co-fractionation Homo sapiens
49 VIPR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 HNRNPU 3192
Co-fractionation Homo sapiens
51 CRELD1 78987
Affinity Capture-MS Homo sapiens
52 GNAI2 2771
Affinity Capture-MS Homo sapiens
53 SLC11A2 4891
Affinity Capture-MS Homo sapiens
54 SLC1A1 6505
Affinity Capture-MS Homo sapiens
55 SLC22A4 6583
Affinity Capture-MS Homo sapiens
56 RANBP6 26953
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 LRRC8B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 AKAP1 8165
Proximity Label-MS Homo sapiens
59 TMCO3 55002
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 TTYH1  
Affinity Capture-MS Homo sapiens
61 CTLA4  
Affinity Capture-MS Homo sapiens
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