Gene description for STK17B
Gene name serine/threonine kinase 17b
Gene symbol STK17B
Other names/aliases DRAK2
Species Homo sapiens
 Database cross references - STK17B
ExoCarta ExoCarta_9262
Entrez Gene 9262
HGNC 11396
MIM 604727
UniProt O94768  
 STK17B identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for STK17B
Molecular Function
    protein serine/threonine kinase activity GO:0004674 IDA
    ATP binding GO:0005524 IDA
    protein kinase activity GO:0004672 ISS
Biological Process
    positive regulation of fibroblast apoptotic process GO:2000271 IMP
    protein phosphorylation GO:0006468 IDA
    apoptotic process GO:0006915 IEA
    intracellular signal transduction GO:0035556 IDA
    protein autophosphorylation GO:0046777 ISS
Subcellular Localization
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 IEA
    plasma membrane GO:0005886 IEA
    nucleus GO:0005634 IDA
    actin cytoskeleton GO:0015629 IEA
 Experiment description of studies that identified STK17B in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for STK17B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CHP1 11261
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
2 STK17B 9262
Invivo Homo sapiens
Affinity Capture-MS Homo sapiens
Invivo Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which STK17B is involved
No pathways found

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