Gene description for TEX2
Gene name testis expressed 2
Gene symbol TEX2
Other names/aliases HT008
TMEM96
Species Homo sapiens
 Database cross references - TEX2
ExoCarta ExoCarta_55852
Vesiclepedia VP_55852
Entrez Gene 55852
HGNC 30884
UniProt Q8IWB9  
 TEX2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for TEX2
Molecular Function
    lipid binding GO:0008289 IBA
Biological Process
    sphingolipid metabolic process GO:0006665 NAS
    lipid transport GO:0006869 IEA
    signal transduction GO:0007165 NAS
Subcellular Localization
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum membrane GO:0005789 IEA
    membrane GO:0016020 NAS
    nuclear membrane GO:0031965 IEA
 Experiment description of studies that identified TEX2 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TEX2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
2 REEP5 7905
Proximity Label-MS Homo sapiens
3 GJD3  
Proximity Label-MS Homo sapiens
4 RAB35 11021
Proximity Label-MS Homo sapiens
5 SLC6A15 55117
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 OR10H2  
Affinity Capture-MS Homo sapiens
7 F2RL1  
Affinity Capture-MS Homo sapiens
8 KIF14 9928
Affinity Capture-MS Homo sapiens
9 METTL7A 25840
Proximity Label-MS Homo sapiens
10 RAB9A 9367
Proximity Label-MS Homo sapiens
11 LRRC59 55379
Proximity Label-MS Homo sapiens
12 RTN3 10313
Affinity Capture-MS Homo sapiens
13 LMAN1 3998
Proximity Label-MS Homo sapiens
14 NUP155 9631
Proximity Label-MS Homo sapiens
15 KIAA1715 80856
Proximity Label-MS Homo sapiens
16 PFN1 5216
Proximity Label-MS Homo sapiens
17 RAB5A 5868
Proximity Label-MS Homo sapiens
18 BCAP31 10134
Proximity Label-MS Homo sapiens
19 HSD3B7 80270
Proximity Label-MS Homo sapiens
20 STIM1 6786
Proximity Label-MS Homo sapiens
21 HSD17B11 51170
Proximity Label-MS Homo sapiens
22 EMD 2010
Proximity Label-MS Homo sapiens
23 LAMP2 3920
Proximity Label-MS Homo sapiens
24 DNAJC25 548645
Proximity Label-MS Homo sapiens
25 FKBP8 23770
Proximity Label-MS Homo sapiens
26 COPE 11316
Affinity Capture-MS Homo sapiens
27 STX4 6810
Proximity Label-MS Homo sapiens
28 FAXC  
Affinity Capture-MS Homo sapiens
29 RTN4 57142
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 SDC2 6383
Affinity Capture-MS Homo sapiens
31 RAB4A 5867
Proximity Label-MS Homo sapiens
32 VAPA 9218
Affinity Capture-MS Homo sapiens
33 PXMP2  
Proximity Label-MS Homo sapiens
34 SLC6A20  
Affinity Capture-MS Homo sapiens
35 FIS1 51024
Proximity Label-MS Homo sapiens
36 C3orf52  
Affinity Capture-MS Homo sapiens
37 SEC62 7095
Proximity Label-MS Homo sapiens
38 ATP2A1 487
Proximity Label-MS Homo sapiens
39 PTPN1 5770
Proximity Label-MS Homo sapiens
40 RAB7A 7879
Proximity Label-MS Homo sapiens
41 RAB11A 8766
Proximity Label-MS Homo sapiens
42 RAB3B 5865
Proximity Label-MS Homo sapiens
43 RPN1 6184
Proximity Label-MS Homo sapiens
44 DNAJC1 64215
Proximity Label-MS Homo sapiens
45 MARCH1  
Affinity Capture-MS Homo sapiens
46 SSR1 6745
Proximity Label-MS Homo sapiens
47 CKAP4 10970
Proximity Label-MS Homo sapiens
48 EFNB2 1948
Affinity Capture-MS Homo sapiens
49 MRAP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 RHOT2 89941
Proximity Label-MS Homo sapiens
51 ATP2A3 489
Affinity Capture-MS Homo sapiens
52 SEC61B 10952
Proximity Label-MS Homo sapiens
53 DERL1 79139
Proximity Label-MS Homo sapiens
54 SLC25A46 91137
Proximity Label-MS Homo sapiens
View the network image/svg+xml



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