Gene description for FAM160A2
Gene name family with sequence similarity 160, member A2
Gene symbol FAM160A2
Other names/aliases C11orf56
Species Homo sapiens
 Database cross references - FAM160A2
ExoCarta ExoCarta_84067
Vesiclepedia VP_84067
Entrez Gene 84067
HGNC 25378
UniProt Q8N612  
 FAM160A2 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for FAM160A2
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    endosome organization GO:0007032 IBA
    endosome organization GO:0007032 IMP
    lysosome organization GO:0007040 IBA
    lysosome organization GO:0007040 IMP
    endosome to lysosome transport GO:0008333 IBA
    endosome to lysosome transport GO:0008333 IMP
    protein transport GO:0015031 IEA
    early endosome to late endosome transport GO:0045022 IBA
    early endosome to late endosome transport GO:0045022 IMP
    protein localization to perinuclear region of cytoplasm GO:1905719 IMP
Subcellular Localization
    FHF complex GO:0070695 IBA
    FHF complex GO:0070695 IDA
 Experiment description of studies that identified FAM160A2 in exosomes
1
Experiment ID 236
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for FAM160A2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATG9A 79065
Proximity Label-MS Homo sapiens
2 GPR17 2840
Affinity Capture-MS Homo sapiens
3 AGTRAP 57085
Two-hybrid Homo sapiens
4 AKTIP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
5 HOOK1  
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
6 TNFSF13B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 RABAC1 10567
Two-hybrid Homo sapiens
8 RTN1 6252
Two-hybrid Homo sapiens
9 HOOK3 84376
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
10 REEP6  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
11 RAB5A 5868
Proximity Label-MS Homo sapiens
12 RTN3 10313
Two-hybrid Homo sapiens
13 DDX58 23586
Affinity Capture-RNA Homo sapiens
View the network image/svg+xml
 Pathways in which FAM160A2 is involved
No pathways found





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