Gene description for HDAC8
Gene name	histone deacetylase 8
Gene symbol	HDAC8
Other names/aliases	CDA07 CDLS5 HD8 HDACL1 MRXS6 RPD3 WTS
Species	Homo sapiens
Database cross references - HDAC8
ExoCarta	ExoCarta_55869
Entrez Gene	55869
HGNC	13315
MIM	300269
UniProt	Q9BY41
HDAC8 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for HDAC8

Molecular Function     metal ion binding GO:0046872 IEA     NAD-dependent histone deacetylase activity (H4-K16 specific) GO:0046970 IEA     NAD-dependent histone deacetylase activity (H3-K14 specific) GO:0032041 IEA     NAD-dependent histone deacetylase activity (H3-K9 specific) GO:0046969 IEA     NAD-dependent histone deacetylase activity (H3-K18 specific) GO:0097372 IEA     transcription factor binding GO:0008134 TAS     histone deacetylase activity GO:0004407 TAS Biological Process     mitotic cell cycle GO:0000278 TAS     chromatin modification GO:0016568 TAS     histone H3-K9 deacetylation GO:1990619 IEA     histone H3-K9 modification GO:0061647 IEA     chromatin organization GO:0006325 TAS     histone H4 deacetylation GO:0070933 IEA     regulation of cohesin localization to chromatin GO:0071922 IMP     chromatin assembly or disassembly GO:0006333 TAS     sister chromatid cohesion GO:0007062 IMP     negative regulation of transcription from RNA polymerase II promoter GO:0000122 TAS     transcription, DNA-templated GO:0006351 IEA Subcellular Localization     nucleoplasm GO:0005654 TAS     cytosol GO:0005829 TAS     nucleus GO:0005634 TAS     nuclear chromosome GO:0000228 TAS     histone deacetylase complex GO:0000118 TAS     cytoplasm GO:0005737 TAS     plasma membrane GO:0005886 IDA