Gene description for IL1RN
Gene name	interleukin 1 receptor antagonist
Gene symbol	IL1RN
Other names/aliases	DIRA ICIL-1RA IL-1RN IL-1ra IL-1ra3 IL1F3 IL1RA IRAP MVCD4
Species	Homo sapiens
Database cross references - IL1RN
ExoCarta	ExoCarta_3557
Entrez Gene	3557
HGNC	6000
MIM	147679
UniProt	P18510
IL1RN identified in exosomes derived from the following tissue/cell type
Urine	19056867

Gene ontology annotations for IL1RN

Molecular Function     interleukin-1 Type II receptor antagonist activity GO:0045353 IDA     interleukin-1 receptor antagonist activity GO:0005152 TAS     interleukin-1 receptor binding GO:0005149 IDA     interleukin-1, Type I receptor binding GO:0005150 IPI     interleukin-1 Type I receptor antagonist activity GO:0045352 IDA     cytokine activity GO:0005125 IBA     interleukin-1, Type II receptor binding GO:0005151 IPI Biological Process     cytokine-mediated signaling pathway GO:0019221 IBA     response to interleukin-4 GO:0070670 IEA     female pregnancy GO:0007565 IEA     response to interleukin-1 GO:0070555 IEA     carboxylic acid metabolic process GO:0019752 IEA     response to starvation GO:0042594 IEA     negative regulation of apoptotic process GO:0043066 IEA     fever generation GO:0001660 IEA     positive regulation of JUN kinase activity GO:0043507 IEA     chronic inflammatory response to antigenic stimulus GO:0002439 IEA     negative regulation of interleukin-1-mediated signaling pathway GO:2000660 IDA     response to drug GO:0042493 IEA     negative regulation of heterotypic cell-cell adhesion GO:0034115 IDA     negative regulation of glutamate secretion GO:0014050 IEA     response to lipopolysaccharide GO:0032496 IEA     cellular response to norepinephrine stimulus GO:0071874 IEA     immune response GO:0006955 NAS     acute-phase response GO:0006953 IDA     negative regulation of cytokine-mediated signaling pathway GO:0001960 IDA     memory GO:0007613 IEA     sensory perception of pain GO:0019233 IEA     negative regulation of membrane potential GO:0045837 IEA     negative regulation of cell migration GO:0030336 IEA     insulin secretion GO:0030073 IEA     response to activity GO:0014823 IEA     response to glucocorticoid GO:0051384 IDA     lipid metabolic process GO:0006629 IEA Subcellular Localization     extracellular space GO:0005615 IDA     intracellular GO:0005622 NAS     extracellular exosome GO:0070062 IDA     cytoplasm GO:0005737 IEA     plasma membrane GO:0005886 TAS