Gene description for B4GALT7
Gene name xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
Gene symbol B4GALT7
Other names/aliases EDSP1
XGALT1
XGPT1
Species Homo sapiens
 Database cross references - B4GALT7
ExoCarta ExoCarta_11285
Entrez Gene 11285
HGNC 930
MIM 604327
UniProt Q9UBV7  
 B4GALT7 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for B4GALT7
Molecular Function
    xylosylprotein 4-beta-galactosyltransferase activity GO:0046525 IDA
    galactosyltransferase activity GO:0008378 IMP
    protein binding GO:0005515 IPI
    manganese ion binding GO:0030145 IDA
    beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity GO:0003831 IDA
Biological Process
    glycosaminoglycan biosynthetic process GO:0006024 IDA
    extracellular fibril organization GO:0043206 IMP
    cellular protein modification process GO:0006464 TAS
    negative regulation of fibroblast proliferation GO:0048147 IMP
    carbohydrate metabolic process GO:0005975 TAS
    proteoglycan metabolic process GO:0006029 IMP
    chondroitin sulfate metabolic process GO:0030204 TAS
    small molecule metabolic process GO:0044281 TAS
    protein N-linked glycosylation GO:0006487 IDA
    glycosaminoglycan metabolic process GO:0030203 TAS
Subcellular Localization
    extracellular matrix GO:0031012 IMP
    Golgi membrane GO:0000139 TAS
    Golgi apparatus GO:0005794 IDA
    Golgi cisterna membrane GO:0032580 IEA
    integral component of membrane GO:0016021 IDA
 Experiment description of studies that identified B4GALT7 in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for B4GALT7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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