Gene description for C1GALT1C1
Gene name C1GALT1-specific chaperone 1
Gene symbol C1GALT1C1
Other names/aliases C1GALT2
C38H2-L1
COSMC
HSPC067
MST143
TNPS
Species Homo sapiens
 Database cross references - C1GALT1C1
ExoCarta ExoCarta_29071
Entrez Gene 29071
HGNC 24338
MIM 300611
UniProt Q96EU7  
 C1GALT1C1 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for C1GALT1C1
Molecular Function
    protein binding GO:0005515 IPI
    polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 TAS
Biological Process
    platelet activation GO:0030168 IEA
    protein O-linked glycosylation GO:0006493 TAS
    positive regulation of transferase activity GO:0051347 IEA
    platelet morphogenesis GO:0036344 IEA
    cellular protein metabolic process GO:0044267 TAS
    O-glycan processing GO:0016266 TAS
    post-translational protein modification GO:0043687 TAS
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    Golgi membrane GO:0000139 TAS
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified C1GALT1C1 in exosomes
1
Experiment ID 66
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD63|CD81
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for C1GALT1C1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which C1GALT1C1 is involved
PathwayEvidenceSource
O-linked glycosylation of mucins TAS Reactome





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