Gene description for OGFOD3
Gene name 2-oxoglutarate and iron-dependent oxygenase domain containing 3
Gene symbol OGFOD3
Other names/aliases C17orf101
Species Homo sapiens
 Database cross references - OGFOD3
ExoCarta ExoCarta_79701
Vesiclepedia VP_79701
Entrez Gene 79701
HGNC 26174
UniProt Q6PK18  
 OGFOD3 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for OGFOD3
Molecular Function
    iron ion binding GO:0005506 IEA
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 IEA
    L-ascorbic acid binding GO:0031418 IEA
    dioxygenase activity GO:0051213 IEA
Subcellular Localization
    membrane GO:0016020 HDA
 Experiment description of studies that identified OGFOD3 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for OGFOD3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ALCAM 214
Cross-Linking-MS (XL-MS) Homo sapiens
2 C1GALT1C1 29071
Affinity Capture-MS Homo sapiens
3 TRIP6 7205
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 MPC2 25874
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 NHLRC3 387921
Affinity Capture-MS Homo sapiens
6 CLGN 1047
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 F2RL1  
Affinity Capture-MS Homo sapiens
8 DDI1  
Affinity Capture-MS Homo sapiens
9 CANX 821
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 PRF1  
Affinity Capture-MS Homo sapiens
11 SLC27A4 10999
Affinity Capture-MS Homo sapiens
12 EIF2AK3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 FOXA1  
Affinity Capture-MS Homo sapiens
14 ROR2 4920
Affinity Capture-MS Homo sapiens
15 LMF1 64788
Affinity Capture-MS Homo sapiens
16 ACP5  
Affinity Capture-MS Homo sapiens
17 HLA-F 3134
Affinity Capture-MS Homo sapiens
18 HLA-B 3106
Affinity Capture-MS Homo sapiens
19 DNAJB9 4189
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 TMEM9 252839
Affinity Capture-MS Homo sapiens
21 ENTPD2 954
Affinity Capture-MS Homo sapiens
22 ST14 6768
Affinity Capture-MS Homo sapiens
23 HLA-C 3107
Affinity Capture-MS Homo sapiens
24 ATP2C1 27032
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 HS6ST2 90161
Affinity Capture-MS Homo sapiens
26 GPC6 10082
Affinity Capture-MS Homo sapiens
27 DGCR2 9993
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which OGFOD3 is involved
No pathways found





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