Gene description for GXYLT1
Gene name glucoside xylosyltransferase 1
Gene symbol GXYLT1
Other names/aliases GLT8D3
Species Homo sapiens
 Database cross references - GXYLT1
ExoCarta ExoCarta_283464
Vesiclepedia VP_283464
Entrez Gene 283464
HGNC 27482
MIM 613321
UniProt Q4G148  
 GXYLT1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Endothelial cells 26027894    
 Gene ontology annotations for GXYLT1
Molecular Function
    UDP-xylosyltransferase activity GO:0035252 IBA
    UDP-xylosyltransferase activity GO:0035252 IDA
    UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity GO:0140563 IEA
Biological Process
    O-glycan processing GO:0016266 IBA
    O-glycan processing GO:0016266 IDA
Subcellular Localization
    membrane GO:0016020 IEA
 Experiment description of studies that identified GXYLT1 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for GXYLT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 XXYLT1 152002
Affinity Capture-MS Homo sapiens
2 EDEM2  
Affinity Capture-MS Homo sapiens
3 NGLY1 55768
Affinity Capture-MS Homo sapiens
4 MOCS3 27304
Affinity Capture-MS Homo sapiens
5 CLGN 1047
Affinity Capture-MS Homo sapiens
6 IL17RA 23765
Affinity Capture-MS Homo sapiens
7 SUN1 23353
Affinity Capture-MS Homo sapiens
8 NPTX1  
Affinity Capture-MS Homo sapiens
9 GPX8 493869
Affinity Capture-MS Homo sapiens
10 TMEM106A  
Affinity Capture-MS Homo sapiens
11 ST14 6768
Affinity Capture-MS Homo sapiens
12 P4HTM  
Affinity Capture-MS Homo sapiens
13 AIFM1 9131
Affinity Capture-MS Homo sapiens
14 CANX 821
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 CLSTN3 9746
Affinity Capture-MS Homo sapiens
16 HSPA13 6782
Affinity Capture-MS Homo sapiens
17 CALR3  
Proximity Label-MS Homo sapiens
18 CHST12 55501
Affinity Capture-MS Homo sapiens
19 POMK  
Affinity Capture-MS Homo sapiens
20 PDIA4 9601
Proximity Label-MS Homo sapiens
21 STIM1 6786
Affinity Capture-MS Homo sapiens
22 EFNA2  
Affinity Capture-MS Homo sapiens
23 SLC39A7 7922
Affinity Capture-MS Homo sapiens
24 PDGFRA 5156
Affinity Capture-MS Homo sapiens
25 SPINT1 6692
Affinity Capture-MS Homo sapiens
26 NOMO1 23420
Affinity Capture-MS Homo sapiens
27 ERLEC1 27248
Affinity Capture-MS Homo sapiens
28 SEMA6B 10501
Affinity Capture-MS Homo sapiens
29 FZD6 8323
Affinity Capture-MS Homo sapiens
30 ADPGK 83440
Affinity Capture-MS Homo sapiens
31 KREMEN2  
Affinity Capture-MS Homo sapiens
32 APLP2 334
Affinity Capture-MS Homo sapiens
33 LRRC59 55379
Proximity Label-MS Homo sapiens
34 OMA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 LAMB3 3914
Affinity Capture-MS Homo sapiens
36 TOR1AIP1 26092
Affinity Capture-MS Homo sapiens
37 OS9 10956
Affinity Capture-MS Homo sapiens
38 EDEM3 80267
Affinity Capture-MS Homo sapiens
39 APP 351
Affinity Capture-MS Homo sapiens
40 SEL1L 6400
Affinity Capture-MS Homo sapiens
41 FKBP14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 EPHA7 2045
Affinity Capture-MS Homo sapiens
43 CHCHD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 SEPN1 57190
Affinity Capture-MS Homo sapiens
45 TAPBP 6892
Affinity Capture-MS Homo sapiens
46 ITGA7 3679
Affinity Capture-MS Homo sapiens
47 HYAL2 8692
Affinity Capture-MS Homo sapiens
48 RPA3 6119
Proximity Label-MS Homo sapiens
49 LRP6 4040
Affinity Capture-MS Homo sapiens
50 FBXO2 26232
Affinity Capture-MS Homo sapiens
51 OGT 8473
Reconstituted Complex Homo sapiens
52 SCGB2A2  
Affinity Capture-MS Homo sapiens
53 HLA-F 3134
Affinity Capture-MS Homo sapiens
54 MSLN 10232
Affinity Capture-MS Homo sapiens
55 ALPP 250
Affinity Capture-MS Homo sapiens
56 ITGB4 3691
Affinity Capture-MS Homo sapiens
57 ASPHD2  
Affinity Capture-MS Homo sapiens
58 MIA3 375056
Affinity Capture-MS Homo sapiens
59 P4HB 5034
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 DSC2 1824
Affinity Capture-MS Homo sapiens
61 EXT2 2132
Affinity Capture-MS Homo sapiens
62 P2RX2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 HLA-DQB1 3119
Affinity Capture-MS Homo sapiens
64 HTR1B  
Affinity Capture-MS Homo sapiens
65 ABHD17B 51104
Affinity Capture-MS Homo sapiens
66 ITGB5 3693
Affinity Capture-MS Homo sapiens
67 HLA-DRB1 3123
Affinity Capture-MS Homo sapiens
68 UBE2J1 51465
Affinity Capture-MS Homo sapiens
69 VIM 7431
Affinity Capture-MS Homo sapiens
70 FGFR4 2264
Affinity Capture-MS Homo sapiens
71 CBWD1 55871
Affinity Capture-MS Homo sapiens
72 CLPTM1 1209
Affinity Capture-MS Homo sapiens
73 SEC61B 10952
Proximity Label-MS Homo sapiens
74 SUN2 25777
Affinity Capture-MS Homo sapiens
75 CERCAM 51148
Affinity Capture-MS Homo sapiens
76 KPRP 448834
Affinity Capture-MS Homo sapiens
77 PCDHB3  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GXYLT1 is involved
No pathways found





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