Gene description for OBSCN
Gene name	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Gene symbol	OBSCN
Other names/aliases	ARHGEF30 UNC89
Species	Homo sapiens
Database cross references - OBSCN
ExoCarta	ExoCarta_84033
Vesiclepedia	VP_84033
Entrez Gene	84033
HGNC	15719
MIM	608616
UniProt	Q5VST9
OBSCN identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for OBSCN

Molecular Function     3-phosphoinositide-dependent protein kinase activity GO:0004676 IEA     DNA-dependent protein kinase activity GO:0004677 IEA     AMP-activated protein kinase activity GO:0004679 IEA     eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 IEA     ribosomal protein S6 kinase activity GO:0004711 IEA     guanyl-nucleotide exchange factor activity GO:0005085 TAS     protein binding GO:0005515 IPI     calmodulin binding GO:0005516 IEA     ATP binding GO:0005524 IEA     phosphatidylinositol-4,5-bisphosphate binding GO:0005546 IDA     phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 IDA     structural constituent of muscle GO:0008307 NAS     phosphatidylinositol-5-phosphate binding GO:0010314 IDA     ankyrin binding GO:0030506 IPI     titin binding GO:0031432 IPI     phosphatidylinositol-3-phosphate binding GO:0032266 IDA     histone H3S10 kinase activity GO:0035175 IEA     histone H3T11 kinase activity GO:0035402 IEA     histone H3T6 kinase activity GO:0035403 IEA     histone H2AXS139 kinase activity GO:0035979 IEA     phosphatidylinositol-3,4-bisphosphate binding GO:0043325 IDA     histone H3S28 kinase activity GO:0044022 IEA     histone H4S1 kinase activity GO:0044023 IEA     histone H2AS1 kinase activity GO:0044024 IEA     histone H2BS14 kinase activity GO:0044025 IEA     metal ion binding GO:0046872 IEA     phosphatidylinositol-4-phosphate binding GO:0070273 IDA     histone H3T3 kinase activity GO:0072354 IEA     histone H2AS121 kinase activity GO:0072371 IEA     Rho-dependent protein serine/threonine kinase activity GO:0072518 IEA     protein serine kinase activity GO:0106310 IEA     histone H2BS36 kinase activity GO:0140823 IEA     histone H3S57 kinase activity GO:0140855 IEA     histone H3T45 kinase activity GO:0140857 IEA     histone H2AT120 kinase activity GO:1990244 IEA Biological Process     chromatin remodeling GO:0006338 IEA     protein localization to M-band GO:0036309 ISS     sarcomere organization GO:0045214 TAS     regulation of small GTPase mediated signal transduction GO:0051056 TAS Subcellular Localization     cytosol GO:0005829 IDA     cytosol GO:0005829 TAS     plasma membrane GO:0005886 IDA     nuclear body GO:0016604 IDA     myofibril GO:0030016 NAS     Z disc GO:0030018 ISS     M band GO:0031430 ISS     sarcolemma GO:0042383 IEA