Gene description for MON2
Gene name MON2 homolog (S. cerevisiae)
Gene symbol MON2
Other names/aliases -
Species Homo sapiens
 Database cross references - MON2
ExoCarta ExoCarta_23041
Vesiclepedia VP_23041
Entrez Gene 23041
HGNC 29177
UniProt Q7Z3U7  
 MON2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for MON2
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    Golgi to endosome transport GO:0006895 ISS
    protein transport GO:0015031 IEA
Subcellular Localization
    cytosol GO:0005829 IEA
    early endosome membrane GO:0031901 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified MON2 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MON2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GJD3  
Proximity Label-MS Homo sapiens
2 UPK2 7379
Affinity Capture-MS Homo sapiens
3 OCLN 100506658
Proximity Label-MS Homo sapiens
4 GJA1 2697
Proximity Label-MS Homo sapiens
5 TRIM66  
Affinity Capture-MS Homo sapiens
6 SPTLC1 10558
Affinity Capture-MS Homo sapiens
7 C9orf78 51759
Affinity Capture-MS Homo sapiens
8 TMEM9B 56674
Affinity Capture-MS Homo sapiens
9 FFAR1  
Affinity Capture-MS Homo sapiens
10 PDE2A  
Affinity Capture-MS Homo sapiens
11 PAAF1 80227
Co-fractionation Homo sapiens
12 B3GAT1  
Proximity Label-MS Homo sapiens
13 B3GNT2 10678
Affinity Capture-MS Homo sapiens
14 HLA-B 3106
Affinity Capture-MS Homo sapiens
15 RAB3B 5865
Proximity Label-MS Homo sapiens
16 OPRM1 4988
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 SLAMF1 6504
Affinity Capture-MS Homo sapiens
18 GGA1 26088
Affinity Capture-Western Homo sapiens
19 TACSTD2 4070
Affinity Capture-MS Homo sapiens
20 F2RL1  
Affinity Capture-MS Homo sapiens
21 CA14 23632
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 EBAG9 9166
Proximity Label-MS Homo sapiens
23 LAMTOR1 55004
Proximity Label-MS Homo sapiens
24 MTNR1B  
Two-hybrid Homo sapiens
25 NUP155 9631
Proximity Label-MS Homo sapiens
26 PFN1 5216
Proximity Label-MS Homo sapiens
27 XPO1 7514
Co-fractionation Homo sapiens
28 FOXA1  
Affinity Capture-MS Homo sapiens
29 PTPRN2  
Affinity Capture-MS Homo sapiens
30 C19orf38  
Affinity Capture-MS Homo sapiens
31 CXADR 1525
Proximity Label-MS Homo sapiens
32 STOM 2040
Affinity Capture-MS Homo sapiens
33 P2RY8  
Affinity Capture-MS Homo sapiens
34 RAB4A 5867
Proximity Label-MS Homo sapiens
35 Klhl21  
Affinity Capture-MS Mus musculus
36 S1PR1 1901
Affinity Capture-MS Homo sapiens
37 GPR182  
Affinity Capture-MS Homo sapiens
38 RAB7A 7879
Proximity Label-MS Homo sapiens
39 STX6 10228
Proximity Label-MS Homo sapiens
40 ELOVL5 60481
Proximity Label-MS Homo sapiens
41 Ppp2r1a 51792
Affinity Capture-MS Mus musculus
42 CD40 958
Affinity Capture-MS Homo sapiens
43 NTRK1 4914
Affinity Capture-MS Homo sapiens
44 SIGLECL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 BTNL9  
Affinity Capture-MS Homo sapiens
46 RAB5A 5868
Proximity Label-MS Homo sapiens
47 ARRDC4  
Affinity Capture-MS Homo sapiens
48 TNFSF8  
Affinity Capture-MS Homo sapiens
49 NPTN 27020
Affinity Capture-MS Homo sapiens
50 HIST1H1E 3008
Co-fractionation Homo sapiens
51 MGARP  
Affinity Capture-MS Homo sapiens
52 CUL3 8452
Affinity Capture-MS Homo sapiens
53 NPY2R  
Affinity Capture-MS Homo sapiens
54 EGFR 1956
Affinity Capture-MS Homo sapiens
55 AQP3  
Affinity Capture-MS Homo sapiens
56 ABHD12 26090
Affinity Capture-MS Homo sapiens
57 Cdc16  
Affinity Capture-MS Mus musculus
58 VSIG4  
Affinity Capture-MS Homo sapiens
59 RPA3 6119
Proximity Label-MS Homo sapiens
60 GPR45  
Affinity Capture-MS Homo sapiens
61 RAB9A 9367
Proximity Label-MS Homo sapiens
62 GOLGA1  
Proximity Label-MS Homo sapiens
63 OBSCN 84033
Affinity Capture-MS Homo sapiens
64 PTPRN  
Affinity Capture-MS Homo sapiens
65 DDRGK1 65992
Affinity Capture-MS Homo sapiens
66 P2RY10  
Affinity Capture-MS Homo sapiens
67 HLA-DQB1 3119
Affinity Capture-MS Homo sapiens
68 TNFSF13B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 PEX3 8504
Proximity Label-MS Homo sapiens
70 HIF1A 3091
Affinity Capture-MS Homo sapiens
71 SDC2 6383
Affinity Capture-MS Homo sapiens
72 GOLGA2 2801
Proximity Label-MS Homo sapiens
73 GGA3 23163
Affinity Capture-Western Homo sapiens
74 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
75 FASN 2194
Negative Genetic Homo sapiens
76 ANKFY1 51479
Co-fractionation Homo sapiens
77 TMEM9 252839
Affinity Capture-MS Homo sapiens
78 ROCK1 6093
Co-fractionation Homo sapiens
79 VASN 114990
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 OPALIN  
Affinity Capture-MS Homo sapiens
81 MFSD4  
Affinity Capture-MS Homo sapiens
82 COMMD5 28991
Affinity Capture-MS Homo sapiens
83 TNFSF14  
Affinity Capture-MS Homo sapiens
84 EFNB1 1947
Affinity Capture-MS Homo sapiens
85 DDX58 23586
Affinity Capture-RNA Homo sapiens
86 GORASP1 64689
Proximity Label-MS Homo sapiens
87 ERGIC2 51290
Proximity Label-MS Homo sapiens
88 PLD3 23646
Affinity Capture-MS Homo sapiens
89 PXN 5829
Proximity Label-MS Homo sapiens
90 RAB11A 8766
Proximity Label-MS Homo sapiens
91 LDLR 3949
Negative Genetic Homo sapiens
92 C9orf72  
Affinity Capture-MS Homo sapiens
93 TAF12  
Affinity Capture-MS Homo sapiens
94 S1PR4  
Affinity Capture-MS Homo sapiens
95 SPINT2 10653
Affinity Capture-MS Homo sapiens
96 CAV1 857
Proximity Label-MS Homo sapiens
97 HLA-C 3107
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which MON2 is involved
No pathways found





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