Gene description for WNT5A
Gene name wingless-type MMTV integration site family, member 5A
Gene symbol WNT5A
Other names/aliases hWNT5A
Species Homo sapiens
 Database cross references - WNT5A
ExoCarta ExoCarta_7474
Vesiclepedia VP_7474
Entrez Gene 7474
HGNC 12784
MIM 164975
UniProt P41221  
 WNT5A identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Chondrocytes 35931686    
Chondrocytes 35931686    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
 Gene ontology annotations for WNT5A
Molecular Function
    frizzled binding GO:0005109 IBA
    frizzled binding GO:0005109 IPI
    frizzled binding GO:0005109 TAS
    receptor tyrosine kinase-like orphan receptor binding GO:0005115 IPI
    cytokine activity GO:0005125 IBA
    protein binding GO:0005515 IPI
    phospholipid binding GO:0005543 TAS
    protein domain specific binding GO:0019904 IEA
    receptor ligand activity GO:0048018 IC
    chemoattractant activity involved in axon guidance GO:1902379 IEA
Biological Process
    establishment of planar polarity GO:0001736 IEA
    somitogenesis GO:0001756 IEA
    kidney development GO:0001822 IEA
    epithelial to mesenchymal transition GO:0001837 IEP
    neural tube closure GO:0001843 IEA
    positive regulation of endothelial cell proliferation GO:0001938 IMP
    heart looping GO:0001947 IEA
    positive regulation of mesenchymal cell proliferation GO:0002053 IEA
    lens development in camera-type eye GO:0002088 ISS
    positive regulation of cytokine production involved in immune response GO:0002720 IMP
    primary heart field specification GO:0003138 IEA
    secondary heart field specification GO:0003139 IEA
    ventricular septum development GO:0003281 IEA
    atrial septum development GO:0003283 IEA
    type B pancreatic cell development GO:0003323 IEA
    pericardium morphogenesis GO:0003344 IEA
    optic cup formation involved in camera-type eye development GO:0003408 ISS
    inflammatory response GO:0006954 IMP
    phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 IMP
    Wnt signaling pathway, calcium modulating pathway GO:0007223 IMP
    Wnt signaling pathway, calcium modulating pathway GO:0007223 NAS
    JNK cascade GO:0007254 IEA
    axon guidance GO:0007411 ISS
    hindgut morphogenesis GO:0007442 IEA
    midgut development GO:0007494 IEA
    protein localization GO:0008104 IDA
    fibroblast growth factor receptor signaling pathway GO:0008543 IEA
    male gonad development GO:0008584 IEP
    anterior/posterior axis specification, embryo GO:0008595 IEA
    mesenchymal cell proliferation GO:0010463 IEA
    positive regulation of endothelial cell migration GO:0010595 IMP
    positive regulation of gene expression GO:0010628 ISS
    epithelial cell migration GO:0010631 IEA
    macrophage derived foam cell differentiation GO:0010742 IMP
    positive regulation of T cell chemotaxis GO:0010820 IMP
    positive regulation of neuron projection development GO:0010976 ISS
    Wnt signaling pathway GO:0016055 IDA
    olfactory bulb interneuron development GO:0021891 ISS
    neuron differentiation GO:0030182 IBA
    neuron differentiation GO:0030182 ISS
    keratinocyte differentiation GO:0030216 IEP
    lung development GO:0030324 IEA
    BMP signaling pathway GO:0030509 IEA
    negative regulation of BMP signaling pathway GO:0030514 IEA
    activation of protein kinase B activity GO:0032148 IDA
    positive regulation of chemokine production GO:0032722 IMP
    positive regulation of type II interferon production GO:0032729 IEA
    positive regulation of interleukin-1 beta production GO:0032731 IMP
    positive regulation of interleukin-1 beta production GO:0032731 ISS
    positive regulation of interleukin-6 production GO:0032755 IMP
    positive regulation of interleukin-8 production GO:0032757 IEA
    positive regulation of tumor necrosis factor production GO:0032760 ISS
    non-canonical Wnt signaling pathway GO:0035567 TAS
    post-anal tail morphogenesis GO:0036342 IEA
    chemoattraction of serotonergic neuron axon GO:0036517 ISS
    chemorepulsion of dopaminergic neuron axon GO:0036518 ISS
    negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 IEA
    wound healing GO:0042060 IDA
    embryonic digit morphogenesis GO:0042733 IEA
    positive regulation of macrophage activation GO:0043032 IMP
    negative regulation of apoptotic process GO:0043066 IDA
    regulation of canonical NF-kappaB signal transduction GO:0043122 ISS
    positive regulation of MAPK cascade GO:0043410 IMP
    positive regulation of JUN kinase activity GO:0043507 IDA
    cell fate commitment GO:0045165 IBA
    establishment of epithelial cell apical/basal polarity GO:0045198 IEA
    negative regulation of fat cell differentiation GO:0045599 IMP
    positive regulation of protein catabolic process GO:0045732 IGI
    positive regulation of angiogenesis GO:0045766 IMP
    positive regulation of ossification GO:0045778 IMP
    positive regulation of endocytosis GO:0045807 IEA
    positive regulation of meiotic nuclear division GO:0045836 IEA
    negative regulation of DNA-templated transcription GO:0045892 IDA
    positive regulation of DNA-templated transcription GO:0045893 IMP
    positive regulation of transcription by RNA polymerase II GO:0045944 IMP
    positive regulation of JNK cascade GO:0046330 IEA
    negative regulation of melanin biosynthetic process GO:0048022 IEA
    positive regulation of fibroblast proliferation GO:0048146 IDA
    paraxial mesoderm formation GO:0048341 IEA
    notochord morphogenesis GO:0048570 IEA
    embryonic skeletal system development GO:0048706 IMP
    genitalia development GO:0048806 IMP
    negative regulation of axon extension involved in axon guidance GO:0048843 IEA
    axon extension involved in axon guidance GO:0048846 IEA
    hypophysis morphogenesis GO:0048850 IEA
    negative regulation of epithelial cell proliferation GO:0050680 IEA
    regulation of inflammatory response GO:0050727 NAS
    positive regulation of inflammatory response GO:0050729 IMP
    regulation of synapse organization GO:0050807 IDA
    regulation of synapse organization GO:0050807 IMP
    positive regulation of NF-kappaB transcription factor activity GO:0051092 IDA
    cartilage development GO:0051216 IEA
    positive regulation of timing of anagen GO:0051885 IEA
    negative regulation of synapse assembly GO:0051964 IEA
    convergent extension involved in axis elongation GO:0060028 IEA
    convergent extension involved in organogenesis GO:0060029 IEA
    uterus development GO:0060065 IEA
    cervix development GO:0060067 IEA
    vagina development GO:0060068 IEA
    canonical Wnt signaling pathway GO:0060070 IBA
    Wnt signaling pathway, planar cell polarity pathway GO:0060071 ISS
    Wnt signaling pathway, planar cell polarity pathway GO:0060071 TAS
    urinary bladder development GO:0060157 IEA
    face development GO:0060324 IMP
    positive regulation of type I interferon-mediated signaling pathway GO:0060340 IDA
    lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 IEA
    mesenchymal-epithelial cell signaling GO:0060638 IEA
    negative regulation of prostatic bud formation GO:0060686 IEA
    mammary gland branching involved in thelarche GO:0060744 IEA
    epithelial cell proliferation involved in mammary gland duct elongation GO:0060750 IEA
    positive regulation of response to cytokine stimulus GO:0060760 IDA
    regulation of branching involved in mammary gland duct morphogenesis GO:0060762 IEA
    mesodermal to mesenchymal transition involved in gastrulation GO:0060809 IEA
    positive regulation of macrophage cytokine production GO:0060907 IMP
    positive regulation of cartilage development GO:0061036 IEA
    secondary palate development GO:0062009 IMP
    thymocyte apoptotic process GO:0070242 IEA
    positive regulation of thymocyte apoptotic process GO:0070245 IEA
    cellular response to lipopolysaccharide GO:0071222 IEP
    cellular response to calcium ion GO:0071277 IEP
    cellular response to retinoic acid GO:0071300 ISS
    cellular response to type II interferon GO:0071346 IEP
    hematopoietic stem cell proliferation GO:0071425 IDA
    cellular response to transforming growth factor beta stimulus GO:0071560 IEP
    negative regulation of mesenchymal cell proliferation GO:0072201 IDA
    primitive streak formation GO:0090009 IEA
    negative regulation of canonical Wnt signaling pathway GO:0090090 IGI
    cochlea morphogenesis GO:0090103 IEA
    melanocyte proliferation GO:0097325 IEA
    presynapse assembly GO:0099054 TAS
    postsynapse assembly GO:0099068 TAS
    postsynaptic modulation of chemical synaptic transmission GO:0099170 IEA
    regulation of postsynapse organization GO:0099175 IDA
    regulation of postsynapse organization GO:0099175 IMP
    regulation of postsynaptic cytosolic calcium ion concentration GO:0099566 IDA
    regulation of postsynaptic cytosolic calcium ion concentration GO:0099566 IMP
    meiotic nuclear division GO:0140013 IEA
    positive regulation of neuron projection arborization GO:0150012 ISS
    positive regulation of protein kinase C activity GO:1900020 IMP
    positive regulation of hematopoietic stem cell proliferation GO:1902035 IEA
    positive regulation of protein localization to synapse GO:1902474 TAS
    excitatory synapse assembly GO:1904861 TAS
    inhibitory synapse assembly GO:1904862 TAS
    negative regulation of cell proliferation in midbrain GO:1904934 NAS
    midbrain dopaminergic neuron differentiation GO:1904948 TAS
    positive regulation of cell-cell adhesion mediated by cadherin GO:2000049 IEA
    positive regulation of non-canonical Wnt signaling pathway GO:2000052 IEA
    positive regulation of apoptotic signaling pathway GO:2001235 ISS
Subcellular Localization
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 IBA
    extracellular space GO:0005615 IDA
    endoplasmic reticulum lumen GO:0005788 TAS
    Golgi lumen GO:0005796 TAS
    plasma membrane GO:0005886 TAS
    cell surface GO:0009986 IEA
    endocytic vesicle membrane GO:0030666 TAS
    clathrin-coated endocytic vesicle membrane GO:0030669 TAS
    collagen-containing extracellular matrix GO:0062023 HDA
    extracellular exosome GO:0070062 TAS
    Schaffer collateral - CA1 synapse GO:0098685 IEA
    postsynapse GO:0098794 IEA
    glutamatergic synapse GO:0098978 IDA
    glutamatergic synapse GO:0098978 IMP
 Experiment description of studies that identified WNT5A in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
8
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for WNT5A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LY86  
Affinity Capture-MS Homo sapiens
2 COL6A1 1291
Affinity Capture-MS Homo sapiens
3 LY6H  
Affinity Capture-MS Homo sapiens
4 C7orf34  
Affinity Capture-MS Homo sapiens
5 PPT1 5538
Affinity Capture-MS Homo sapiens
6 PROS1 5627
Affinity Capture-MS Homo sapiens
7 NPTX1  
Affinity Capture-MS Homo sapiens
8 CCL3L1  
Affinity Capture-MS Homo sapiens
9 SLC31A1 1317
Affinity Capture-MS Homo sapiens
10 PITX2  
Co-localization Homo sapiens
11 FZD2 2535
Affinity Capture-Western Homo sapiens
12 DEFA1 1667
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 LCN6  
Affinity Capture-MS Homo sapiens
14 NOTCH2 4853
Affinity Capture-MS Homo sapiens
15 LDLRAD1  
Affinity Capture-MS Homo sapiens
16 FMR1 2332
Affinity Capture-MS Homo sapiens
17 C1QA 712
Affinity Capture-MS Homo sapiens
18 WNT7A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 PDGFRA 5156
Affinity Capture-MS Homo sapiens
20 WNT4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 CD1A 909
Affinity Capture-MS Homo sapiens
22 CNNM4 26504
Affinity Capture-MS Homo sapiens
23 TMEM45A  
Affinity Capture-MS Homo sapiens
24 FZD1 8321
Affinity Capture-Western Homo sapiens
25 SLC30A7 148867
Affinity Capture-MS Homo sapiens
26 ANTXR1 84168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 GGT7 2686
Affinity Capture-MS Homo sapiens
28 KLRG2 346689
Affinity Capture-MS Homo sapiens
29 WLS 79971
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 POTEF 728378
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 EPHA7 2045
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 CLEC12B  
Affinity Capture-MS Homo sapiens
33 CHRNB2  
Affinity Capture-MS Homo sapiens
34 MSMB  
Affinity Capture-MS Homo sapiens
35 HPN  
Affinity Capture-MS Homo sapiens
36 MKRN2 23609
Affinity Capture-RNA Homo sapiens
37 LMF1 64788
Affinity Capture-MS Homo sapiens
38 SDF2L1 23753
Affinity Capture-MS Homo sapiens
39 LRP6 4040
Affinity Capture-Western Homo sapiens
40 SNX8 29886
Affinity Capture-MS Homo sapiens
41 WNT5B 81029
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 HSPA5 3309
Affinity Capture-MS Homo sapiens
43 SCGB2A2  
Affinity Capture-MS Homo sapiens
44 PSCA 8000
Affinity Capture-MS Homo sapiens
45 TRAPPC2L 51693
Affinity Capture-MS Homo sapiens
46 FZD5 7855
Co-localization Homo sapiens
47 TCTN2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 PTPRK 5796
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 LYPD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 PROC 5624
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 ST14 6768
Affinity Capture-MS Homo sapiens
52 HSPD1 3329
Affinity Capture-MS Homo sapiens
53 NUCKS1 64710
Cross-Linking-MS (XL-MS) Homo sapiens
54 GAS6 2621
Affinity Capture-MS Homo sapiens
55 FSTL1 11167
Affinity Capture-MS Homo sapiens
56 WNT16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 ASAH1 427
Affinity Capture-MS Homo sapiens
58 IGFL3  
Affinity Capture-MS Homo sapiens
59 PLA2G10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 MYCBP2 23077
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which WNT5A is involved
PathwayEvidenceSource
Asymmetric localization of PCP proteins TAS Reactome
Beta-catenin independent WNT signaling TAS Reactome
Beta-catenin independent WNT signaling IEA Reactome
Ca2+ pathway TAS Reactome
Ca2+ pathway IEA Reactome
Cargo recognition for clathrin-mediated endocytosis TAS Reactome
Class B/2 (Secretin family receptors) IEA Reactome
Clathrin-mediated endocytosis TAS Reactome
Disease IEA Reactome
Disease TAS Reactome
GPCR ligand binding IEA Reactome
Infectious disease IEA Reactome
Infectious disease TAS Reactome
Killing mechanisms IEA Reactome
Killing mechanisms TAS Reactome
Leishmania infection IEA Reactome
Leishmania infection TAS Reactome
Membrane Trafficking TAS Reactome
Negative regulation of TCF-dependent signaling by WNT ligand antagonists IEA Reactome
Parasitic Infection Pathways IEA Reactome
Parasitic Infection Pathways TAS Reactome
PCP/CE pathway IEA Reactome
PCP/CE pathway TAS Reactome
Signal Transduction TAS Reactome
Signal Transduction IEA Reactome
Signaling by GPCR IEA Reactome
Signaling by WNT TAS Reactome
Signaling by WNT IEA Reactome
TCF dependent signaling in response to WNT IEA Reactome
TCF dependent signaling in response to WNT TAS Reactome
Vesicle-mediated transport TAS Reactome
WNT ligand biogenesis and trafficking TAS Reactome
WNT ligand biogenesis and trafficking IEA Reactome
WNT5:FZD7-mediated leishmania damping IEA Reactome
WNT5:FZD7-mediated leishmania damping TAS Reactome
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 TAS Reactome
WNT5A-dependent internalization of FZD4 TAS Reactome





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