Gene description for FZD5
Gene name	frizzled class receptor 5
Gene symbol	FZD5
Other names/aliases	C2orf31 HFZ5
Species	Homo sapiens
Database cross references - FZD5
ExoCarta	ExoCarta_7855
Vesiclepedia	VP_7855
Entrez Gene	7855
HGNC	4043
MIM	601723
UniProt	Q13467
FZD5 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Hepatocellular carcinoma cells	26054723
Hepatocytes	26054723

Gene ontology annotations for FZD5

Molecular Function     Wnt-activated receptor activity GO:0042813 IC     protein binding GO:0005515 IPI     Wnt-protein binding GO:0017147 IPI     protein kinase binding GO:0019901 IPI     ubiquitin protein ligase binding GO:0031625 IPI     G-protein coupled receptor activity GO:0004930 IBA Biological Process     embryonic camera-type eye development GO:0031076 IEA     regulation of bicellular tight junction assembly GO:2000810 IEA     angiogenesis GO:0001525 IEA     chorionic trophoblast cell differentiation GO:0060718 IEA     Spemann organizer formation GO:0060061 IDA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IGI     embryonic axis specification GO:0000578 IDA     positive regulation of JUN kinase activity GO:0043507 IEA     non-canonical Wnt signaling pathway GO:0035567 IBA     Wnt signaling pathway involved in dorsal/ventral axis specification GO:0044332 IDA     canonical Wnt signaling pathway GO:0060070 IMP     syncytiotrophoblast cell differentiation involved in labyrinthine layer development GO:0060715 IEA     positive regulation of canonical Wnt signaling pathway GO:0090263 TAS     positive regulation of T cell cytokine production GO:0002726 IDA     negative regulation of cell proliferation GO:0008285 IEA     cell maturation GO:0048469 IEA     post-embryonic camera-type eye development GO:0031077 IEA     regulation of chorionic trophoblast cell proliferation GO:1901382 IEA     branching involved in labyrinthine layer morphogenesis GO:0060670 IEA     cellular response to molecule of bacterial origin GO:0071219 IDA     G-protein coupled receptor signaling pathway GO:0007186 IEA     apoptotic process involved in morphogenesis GO:0060561 IEA     regulation of mitochondrion degradation GO:1903146 IMP     neuron differentiation GO:0030182 ISS     T cell differentiation in thymus GO:0033077 IEA     positive regulation of protein targeting to mitochondrion GO:1903955 IMP     labyrinthine layer blood vessel development GO:0060716 IEA     anterior/posterior axis specification, embryo GO:0008595 IDA     positive regulation of interferon-gamma production GO:0032729 IMP Subcellular Localization     integral component of membrane GO:0016021 IBA     perinuclear region of cytoplasm GO:0048471 IEA     cell surface GO:0009986 IDA     bicellular tight junction GO:0005923 IEA     plasma membrane GO:0005886 TAS     early endosome membrane GO:0031901 TAS     Golgi membrane GO:0000139 IEA     clathrin-coated endocytic vesicle membrane GO:0030669 TAS