Gene description for RPS6KA6
Gene name	ribosomal protein S6 kinase, 90kDa, polypeptide 6
Gene symbol	RPS6KA6
Other names/aliases	PP90RSK4 RSK4
Species	Homo sapiens
Database cross references - RPS6KA6
ExoCarta	ExoCarta_27330
Entrez Gene	27330
HGNC	10435
MIM	300303
UniProt	Q9UK32
RPS6KA6 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells	20124223

Gene ontology annotations for RPS6KA6

Molecular Function     ATP binding GO:0005524 IEA     protein kinase activity GO:0004672 TAS     magnesium ion binding GO:0000287 IEA     ribosomal protein S6 kinase activity GO:0004711 IBA Biological Process     negative regulation of ERK1 and ERK2 cascade GO:0070373 ISS     signal transduction GO:0007165 TAS     negative regulation of embryonic development GO:0045992 ISS     central nervous system development GO:0007417 TAS     DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 IMP     protein phosphorylation GO:0006468 IBA     negative regulation of mesoderm development GO:2000381 ISS     synaptic transmission GO:0007268 TAS     axon guidance GO:0007411 TAS     regulation of translation GO:0006417 IBA Subcellular Localization     cytoplasm GO:0005737 IBA     cytosol GO:0005829 TAS     nucleoplasm GO:0005654 TAS     mitochondrion GO:0005739 IDA     nucleolus GO:0005730 IDA     nucleus GO:0005634 IDA