Gene description for ADIRF
Gene name adipogenesis regulatory factor
Gene symbol ADIRF
Other names/aliases AFRO
APM2
C10orf116
apM-2
Species Homo sapiens
 Database cross references - ADIRF
ExoCarta ExoCarta_10974
Entrez Gene 10974
HGNC 24043
UniProt Q15847  
 ADIRF identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for ADIRF
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    cell differentiation GO:0030154 IEA
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA
    regulation of response to drug GO:2001023 IDA
    cellular response to radiation GO:0071478 IDA
    positive regulation of fat cell differentiation GO:0045600 IDA
    transcription, DNA-templated GO:0006351 IEA
    cellular response to cisplatin GO:0072719 IDA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    extracellular exosome GO:0070062 IDA
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified ADIRF in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for ADIRF
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ADIRF is involved
No pathways found





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