Gene description for DHX34
Gene name DEAH (Asp-Glu-Ala-His) box polypeptide 34
Gene symbol DHX34
Other names/aliases DDX34
HRH1
Species Homo sapiens
 Database cross references - DHX34
ExoCarta ExoCarta_9704
Entrez Gene 9704
HGNC 16719
MIM 615475
UniProt Q14147  
 DHX34 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for DHX34
Molecular Function
    ATP binding GO:0005524 IEA
    ATP-dependent RNA helicase activity GO:0004004 IBA
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    RNA processing GO:0006396 IBA
    nuclear-transcribed mRNA catabolic process GO:0000956 IMP
    negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:2000623 IMP
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 IBA
Subcellular Localization
    membrane GO:0016020 IDA
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified DHX34 in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for DHX34
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 POLA2  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which DHX34 is involved
No pathways found





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