Gene description for C1orf159
Gene name chromosome 1 open reading frame 159
Gene symbol C1orf159
Other names/aliases -
Species Homo sapiens
 Database cross references - C1orf159
ExoCarta ExoCarta_54991
Vesiclepedia VP_54991
Entrez Gene 54991
HGNC 26062
UniProt Q96HA4  
 C1orf159 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for C1orf159
Subcellular Localization
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified C1orf159 in exosomes
1
Experiment ID 235
MISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Enriched markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for C1orf159
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which C1orf159 is involved
No pathways found





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