Gene description for ICAM5
Gene name intercellular adhesion molecule 5, telencephalin
Gene symbol ICAM5
Other names/aliases TLCN
Species Homo sapiens
 Database cross references - ICAM5
ExoCarta ExoCarta_7087
Entrez Gene 7087
HGNC 5348
MIM 601852
UniProt Q9UMF0  
 ICAM5 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for ICAM5
Molecular Function
    protein binding GO:0005515 IPI
    integrin binding GO:0005178 IBA
Biological Process
    phagocytosis GO:0006909 IEA
    single organismal cell-cell adhesion GO:0016337 IEA
    cell adhesion GO:0007155 IBA
Subcellular Localization
    plasma membrane GO:0005886 TAS
    integral component of plasma membrane GO:0005887 TAS
 Experiment description of studies that identified ICAM5 in exosomes
Experiment ID 126
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Antibody array
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for ICAM5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ITGB2 3689
Invitro Homo sapiens
2 ITGAL 3683
Invitro Homo sapiens
3 PSEN2  
Reconstituted Complex Homo sapiens
4 PSEN1  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which ICAM5 is involved
No pathways found

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