Gene description for SLC38A5
Gene name solute carrier family 38, member 5
Gene symbol SLC38A5
Other names/aliases JM24
SN2
SNAT5
pp7194
Species Homo sapiens
 Database cross references - SLC38A5
ExoCarta ExoCarta_92745
Entrez Gene 92745
HGNC 18070
MIM 300649
UniProt Q8WUX1  
 SLC38A5 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for SLC38A5
Molecular Function
    glycine transmembrane transporter activity GO:0015187 IBA
Biological Process
    transmembrane transport GO:0055085 TAS
    amino acid transport GO:0006865 TAS
    glycine transport GO:0015816 IBA
    amino acid transmembrane transport GO:0003333 IBA
    ion transport GO:0006811 TAS
Subcellular Localization
    integral component of plasma membrane GO:0005887 IBA
    plasma membrane GO:0005886 TAS
 Experiment description of studies that identified SLC38A5 in exosomes
1
Experiment ID 191
ISEV standards
✘ EV Biophysical techniques
✔
Alix
EV Cytosolic markers
✔
CD81|CD9
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SLC38A5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC38A5 is involved
PathwayEvidenceSource
Amino acid transport across the plasma membrane TAS Reactome





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