Gene description for COG5
Gene name component of oligomeric golgi complex 5
Gene symbol COG5
Other names/aliases CDG2I
GOLTC1
GTC90
Species Homo sapiens
 Database cross references - COG5
ExoCarta ExoCarta_10466
Entrez Gene 10466
HGNC 14857
MIM 606821
UniProt Q9UP83  
 COG5 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for COG5
Molecular Function
    molecular_function GO:0003674 ND
    protein binding GO:0005515 IPI
Biological Process
    intra-Golgi vesicle-mediated transport GO:0006891 NAS
    protein transport GO:0015031 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    Golgi membrane GO:0000139 IEA
    membrane GO:0016020 IDA
    Golgi transport complex GO:0017119 NAS
    cytosol GO:0005829 IEA
    Golgi apparatus GO:0005794 IDA
 Experiment description of studies that identified COG5 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COG5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 COG7 91949
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
2 MEFV  
Two-hybrid Homo sapiens
3 COG4 25839
Reconstituted Complex Homo sapiens
Invivo Homo sapiens
Invivo Homo sapiens
Invitro Homo sapiens
Invitro Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which COG5 is involved
No pathways found





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