Gene description for COG7
Gene name component of oligomeric golgi complex 7
Gene symbol COG7
Other names/aliases CDG2E
Species Homo sapiens
 Database cross references - COG7
ExoCarta ExoCarta_91949
Entrez Gene 91949
HGNC 18622
MIM 606978
UniProt P83436  
 COG7 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for COG7
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    intracellular protein transport GO:0006886 IMP
    protein stabilization GO:0050821 IMP
    protein localization to organelle GO:0033365 IMP
    protein glycosylation GO:0006486 IMP
    retrograde vesicle-mediated transport, Golgi to ER GO:0006890 IMP
    protein localization to Golgi apparatus GO:0034067 IMP
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    Golgi transport complex GO:0017119 IDA
    Golgi apparatus GO:0005794 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
    nucleolus GO:0005730 IDA
 Experiment description of studies that identified COG7 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COG7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 COG5 10466
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
2 COG4 25839
Invivo Homo sapiens
Invivo Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which COG7 is involved
No pathways found





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