Gene description for POC1B
Gene name POC1 centriolar protein B
Gene symbol POC1B
Other names/aliases CORD20
PIX1
TUWD12
WDR51B
Species Homo sapiens
 Database cross references - POC1B
ExoCarta ExoCarta_282809
Entrez Gene 282809
HGNC 30836
MIM 614784
UniProt Q8TC44  
 POC1B identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for POC1B
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    cilium assembly GO:0042384 IMP
    retina homeostasis GO:0001895 IMP
    cell proliferation GO:0008283 IMP
Subcellular Localization
    ciliary basal body GO:0036064 IDA
    centriole GO:0005814 IDA
    centrosome GO:0005813 IDA
    spindle pole GO:0000922 IDA
 Experiment description of studies that identified POC1B in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for POC1B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which POC1B is involved
No pathways found





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