Gene description for CEP97
Gene name centrosomal protein 97kDa
Gene symbol CEP97
Other names/aliases 2810403B08Rik
LRRIQ2
Species Homo sapiens
 Database cross references - CEP97
ExoCarta ExoCarta_79598
Vesiclepedia VP_79598
Entrez Gene 79598
HGNC 26244
MIM 615864
UniProt Q8IW35  
 CEP97 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells 25844599    
 Gene ontology annotations for CEP97
Molecular Function
    protein binding GO:0005515 IPI
    calmodulin binding GO:0005516 IEA
Biological Process
    cell projection organization GO:0030030 IEA
    regulation of mitotic spindle assembly GO:1901673 IMP
    negative regulation of cilium assembly GO:1902018 IBA
    negative regulation of cilium assembly GO:1902018 IMP
Subcellular Localization
    centrosome GO:0005813 IBA
    centrosome GO:0005813 IDA
    centriole GO:0005814 IDA
    cytosol GO:0005829 TAS
    protein-containing complex GO:0032991 IDA
 Experiment description of studies that identified CEP97 in exosomes
1
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
 Protein-protein interactions for CEP97
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 VPS35 55737
Affinity Capture-MS Homo sapiens
2 AP2B1 163
Proximity Label-MS Homo sapiens
3 SNAP23 8773
Affinity Capture-MS Homo sapiens
4 SORL1 6653
Affinity Capture-MS Homo sapiens
5 ARPC2 10109
Affinity Capture-MS Homo sapiens
6 D2HGDH 728294
Affinity Capture-MS Homo sapiens
7 GOLGA1  
Proximity Label-MS Homo sapiens
8 CALM1 801
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 CAND1 55832
Affinity Capture-MS Homo sapiens
10 LTN1 26046
Affinity Capture-MS Homo sapiens
11 NEDD1 121441
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 MRFAP1L1  
Affinity Capture-MS Homo sapiens
13 CDC16 8881
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 TRMU  
Affinity Capture-MS Homo sapiens
15 ACTR3 10096
Affinity Capture-MS Homo sapiens
16 RFXANK  
Affinity Capture-MS Homo sapiens
17 CADPS  
Affinity Capture-MS Homo sapiens
18 B4GALT2  
Affinity Capture-MS Homo sapiens
19 CALM3 808
Affinity Capture-MS Homo sapiens
20 POC1B 282809
Co-localization Homo sapiens
21 YWHAG 7532
Affinity Capture-MS Homo sapiens
22 ATG7 10533
Affinity Capture-MS Homo sapiens
23 POLR2C 5432
Proximity Label-MS Homo sapiens
24 LHX4  
Affinity Capture-MS Homo sapiens
25 AMOT  
Proximity Label-MS Homo sapiens
26 Cep120  
Affinity Capture-MS Mus musculus
27 NINL  
Proximity Label-MS Homo sapiens
28 CEP44  
Co-localization Homo sapiens
29 PFN1 5216
Proximity Label-MS Homo sapiens
30 KRT8 3856
Proximity Label-MS Homo sapiens
31 IQCB1  
Affinity Capture-MS Homo sapiens
32 KLHL34  
Affinity Capture-MS Homo sapiens
33 MYCBPAP 84073
Affinity Capture-MS Homo sapiens
34 LYN 4067
Affinity Capture-MS Homo sapiens
35 MAPRE1 22919
Affinity Capture-MS Homo sapiens
36 Cep104  
Affinity Capture-MS Mus musculus
37 TUBA1B 10376
Affinity Capture-MS Homo sapiens
38 NTRK1 4914
Affinity Capture-MS Homo sapiens
39 PLK1 5347
Affinity Capture-MS Homo sapiens
40 RPA4  
Proximity Label-MS Homo sapiens
41 STIL  
Proximity Label-MS Homo sapiens
42 CEP76  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
43 AGPS 8540
Proximity Label-MS Homo sapiens
44 NLK  
Affinity Capture-MS Homo sapiens
45 UBXN6 80700
Affinity Capture-MS Homo sapiens
46 Cep290  
Affinity Capture-MS Mus musculus
47 NEURL4  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
48 Ccp110  
Affinity Capture-MS Mus musculus
49 CEP135  
Proximity Label-MS Homo sapiens
50 GNB4 59345
Affinity Capture-MS Homo sapiens
51 XPO1 7514
Affinity Capture-MS Homo sapiens
52 AURKA 6790
Affinity Capture-MS Homo sapiens
53 ACTBL2 345651
Affinity Capture-MS Homo sapiens
54 CCP110  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 TUBB4B 10383
Affinity Capture-MS Homo sapiens
56 HOOK3 84376
Proximity Label-MS Homo sapiens
57 SASS6 163786
Proximity Label-MS Homo sapiens
58 MAATS1  
Affinity Capture-MS Homo sapiens
59 TUBA4A 7277
Affinity Capture-MS Homo sapiens
60 ABTB2 25841
Affinity Capture-MS Homo sapiens
61 SOHLH1  
Affinity Capture-MS Homo sapiens
62 AMZ1  
Affinity Capture-MS Homo sapiens
63 MRFAP1  
Affinity Capture-MS Homo sapiens
64 UNC119 9094
Affinity Capture-MS Homo sapiens
65 NDC80 10403
Proximity Label-MS Homo sapiens
66 GAS2L2  
Affinity Capture-MS Homo sapiens
67 SF3B3 23450
Affinity Capture-MS Homo sapiens
68 Nedd1  
Affinity Capture-MS Mus musculus
69 PCM1 5108
Proximity Label-MS Homo sapiens
70 RASSF7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 KRT2 3849
Affinity Capture-MS Homo sapiens
72 Plk1  
Affinity Capture-MS Mus musculus
73 FTL 2512
Affinity Capture-MS Homo sapiens
74 KRT18 3875
Proximity Label-MS Homo sapiens
75 SUGT1 10910
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 KIF24  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 CEP290  
Affinity Capture-Western Homo sapiens
78 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
79 TUBG1 7283
Co-localization Homo sapiens
80 TRIM52  
Affinity Capture-MS Homo sapiens
81 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
82 ANAPC2 29882
Proximity Label-MS Homo sapiens
83 KRT38 8687
Affinity Capture-MS Homo sapiens
84 INF2 64423
Affinity Capture-MS Homo sapiens
85 C16orf72 29035
Affinity Capture-MS Homo sapiens
86 GALNT9  
Affinity Capture-MS Homo sapiens
87 PXN 5829
Proximity Label-MS Homo sapiens
88 FAM83A  
Affinity Capture-MS Homo sapiens
89 PIPSL 266971
Affinity Capture-MS Homo sapiens
90 CCT8L2  
Affinity Capture-MS Homo sapiens
91 NIN 51199
Proximity Label-MS Homo sapiens
View the network image/svg+xml



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