Gene description for CEP97
Gene name centrosomal protein 97kDa
Gene symbol CEP97
Other names/aliases 2810403B08Rik
LRRIQ2
Species Homo sapiens
 Database cross references - CEP97
ExoCarta ExoCarta_79598
Entrez Gene 79598
HGNC 26244
MIM 615864
UniProt Q8IW35  
 CEP97 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells 25844599    
 Gene ontology annotations for CEP97
Molecular Function
    calmodulin binding GO:0005516 IEA
    protein binding GO:0005515 IPI
Biological Process
    organelle organization GO:0006996 TAS
    cell projection organization GO:0030030 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 TAS
    centrosome GO:0005813 IDA
    microtubule organizing center GO:0005815 IDA
    protein complex GO:0043234 IDA
 Experiment description of studies that identified CEP97 in exosomes
1
Experiment ID 275
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|RAB5A
EV Cytosolic markers
CD9|CD82|CD63|CD81
EV Membrane markers
AIF
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
 Protein-protein interactions for CEP97
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CEP97 is involved
PathwayEvidenceSource
Anchoring of the basal body to the plasma membrane TAS Reactome





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