Experiment description of studies that identified MIIP in exosomes

1 Experiment ID 236 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for MIIP

Protein Interactor ExoCarta ID Identification method PubMed Species 1 ARRB1 408 Affinity Capture-MS Homo sapiens 2 LIMK1 3984 Affinity Capture-MS Homo sapiens 3 OIP5   Two-hybrid Homo sapiens 4 ARRB2 409 Affinity Capture-MS Homo sapiens 5 GRN 2896 Affinity Capture-MS Homo sapiens 6 STK16 8576 Two-hybrid Homo sapiens 7 BCAS2 10286 Two-hybrid Homo sapiens 8 FRS3 10817 Two-hybrid Homo sapiens 9 KCTD9   Two-hybrid Homo sapiens 10 YWHAB 7529 Affinity Capture-MS Homo sapiens 11 AES 166 Two-hybrid Homo sapiens 12 CCDC120   Two-hybrid Homo sapiens 13 HDAC6 10013 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 14 ZDHHC17 23390 Two-hybrid Homo sapiens 15 TEKT4   Two-hybrid Homo sapiens 16 PPP1CA 5499 Two-hybrid Homo sapiens 17 KRT34   Two-hybrid Homo sapiens 18 TRIM55   Two-hybrid Homo sapiens 19 UBR3   Affinity Capture-MS Homo sapiens 20 MOB2 81532 Two-hybrid Homo sapiens 21 OTX1   Two-hybrid Homo sapiens 22 ZNF417   Two-hybrid Homo sapiens 23 APEX1 328 Affinity Capture-RNA Homo sapiens 24 POC1A   Affinity Capture-MS Homo sapiens 25 YWHAE 7531 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 CYSRT1 375791 Two-hybrid Homo sapiens 27 CEP135   Proximity Label-MS Homo sapiens 28 TCHP   Two-hybrid Homo sapiens 29 MLLT3 4300 Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens 30 YWHAQ 10971 Affinity Capture-MS Homo sapiens 31 NMT2 9397 Affinity Capture-MS Homo sapiens 32 USHBP1   Two-hybrid Homo sapiens 33 POC1B 282809 Affinity Capture-MS Homo sapiens 34 YWHAG 7532 Affinity Capture-MS Homo sapiens 35 EIF3E 3646 Two-hybrid Homo sapiens 36 TRIM63   Two-hybrid Homo sapiens 37 KPRP 448834 Two-hybrid Homo sapiens 38 MED28   Two-hybrid Homo sapiens View the network

Pathways in which MIIP is involved

No pathways found