Experiment description of studies that identified PHYHIP in exosomes

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for PHYHIP

Protein Interactor ExoCarta ID Identification method PubMed Species 1 NDUFV3 4731 Two-hybrid Homo sapiens 2 TRIP6 7205 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 METTL18   Two-hybrid Homo sapiens 4 CA10   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 PRKD2 25865 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 EEF1A1 1915 Two-hybrid Homo sapiens 7 KIF15 56992 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 C14orf1 11161 Two-hybrid Homo sapiens 9 ANKRD12   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 10 PPIE 10450 Two-hybrid Homo sapiens 11 PHYHIPL   Affinity Capture-MS Homo sapiens 12 ANKRD40 91369 Affinity Capture-MS Homo sapiens 13 TMEM255B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 ZZEF1 23140 Two-hybrid Homo sapiens 15 MED8   Two-hybrid Homo sapiens 16 MARCH7   Affinity Capture-MS Homo sapiens 17 Supt5   Two-hybrid Mus musculus 18 PRMT5 10419 Two-hybrid Homo sapiens 19 HDAC11   Two-hybrid Homo sapiens 20 WDR89   Two-hybrid Homo sapiens 21 FAM131A   Two-hybrid Homo sapiens 22 S100A13 6284 Two-hybrid Homo sapiens 23 PAQR5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 PTRH2 51651 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 25 MAGED4B   Two-hybrid Homo sapiens 26 MSI2 124540 Affinity Capture-MS Homo sapiens 27 NDRG1 10397 Two-hybrid Homo sapiens 28 COPS6 10980 Two-hybrid Homo sapiens 29 TTR 7276 Two-hybrid Homo sapiens 30 LIMD1 8994 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 31 PARL   Affinity Capture-MS Homo sapiens 32 PNPLA2   Two-hybrid Homo sapiens 33 COG7 91949 Affinity Capture-MS Homo sapiens 34 TUBB1 81027 Affinity Capture-MS Homo sapiens 35 TUBB8 347688 Affinity Capture-MS Homo sapiens 36 SMARCC2 6601 Two-hybrid Homo sapiens View the network

Pathways in which PHYHIP is involved

No pathways found