Gene description for SLC33A1
Gene name solute carrier family 33 (acetyl-CoA transporter), member 1
Gene symbol SLC33A1
Other names/aliases ACATN
AT-1
AT1
CCHLND
SPG42
Species Homo sapiens
 Database cross references - SLC33A1
ExoCarta ExoCarta_9197
Entrez Gene 9197
HGNC 95
MIM 603690
UniProt O00400  
 SLC33A1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for SLC33A1
Molecular Function
    solute:proton symporter activity GO:0015295 IBA
    acetyl-CoA transporter activity GO:0008521 IEA
Biological Process
    BMP signaling pathway GO:0030509 IDA
    SMAD protein signal transduction GO:0060395 IDA
    transmembrane transport GO:0055085 TAS
    proton transport GO:0015992 IBA
    acetyl-CoA transport GO:0015876 TAS
    transport GO:0006810 TAS
Subcellular Localization
    membrane GO:0016020 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
    Golgi membrane GO:0000139 TAS
    integral component of plasma membrane GO:0005887 TAS
 Experiment description of studies that identified SLC33A1 in exosomes
1
Experiment ID 235
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for SLC33A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC33A1 is involved
PathwayEvidenceSource
Transport of vitamins, nucleosides, and related molecules TAS Reactome





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