Gene description for IFFO2
Gene name intermediate filament family orphan 2
Gene symbol IFFO2
Other names/aliases -
Species Homo sapiens
 Database cross references - IFFO2
ExoCarta ExoCarta_126917
Entrez Gene 126917
HGNC 27006
UniProt Q5TF58  
 IFFO2 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for IFFO2
Molecular Function
    structural molecule activity GO:0005198 IEA
Subcellular Localization
    intermediate filament GO:0005882 IEA
 Experiment description of studies that identified IFFO2 in exosomes
1
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for IFFO2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which IFFO2 is involved
No pathways found





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