Gene description for IFFO2
Gene name intermediate filament family orphan 2
Gene symbol IFFO2
Other names/aliases -
Species Homo sapiens
 Database cross references - IFFO2
ExoCarta ExoCarta_126917
Vesiclepedia VP_126917
Entrez Gene 126917
HGNC 27006
UniProt Q5TF58  
 IFFO2 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for IFFO2
Subcellular Localization
    intermediate filament GO:0005882 IEA
 Experiment description of studies that identified IFFO2 in sEVs
1
Experiment ID 236
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for IFFO2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 XRCC4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 Dynll1 56455
Affinity Capture-MS Mus musculus
4 GFAP 2670
Proximity Label-MS Homo sapiens
5 FGFR2 2263
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 CCDC96  
Affinity Capture-MS Homo sapiens
7 DYNLL2 140735
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 PPP1R13B  
Affinity Capture-MS Homo sapiens
9 PRPH 5630
Proximity Label-MS Homo sapiens
10 NIN 51199
Proximity Label-MS Homo sapiens
11 LURAP1  
Affinity Capture-MS Homo sapiens
12 DYNLL1 8655
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 FAS 355
Proximity Label-MS Homo sapiens
14 MAGEA9  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which IFFO2 is involved
No pathways found





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