Gene description for CUEDC1
Gene name CUE domain containing 1
Gene symbol CUEDC1
Other names/aliases -
Species Homo sapiens
 Database cross references - CUEDC1
ExoCarta ExoCarta_404093
Vesiclepedia VP_404093
Entrez Gene 404093
HGNC 31350
UniProt Q9NWM3  
 CUEDC1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for CUEDC1
Molecular Function
    protein binding GO:0005515 IPI
    ubiquitin binding GO:0043130 IEA
 Experiment description of studies that identified CUEDC1 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for CUEDC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPS14 6208
Affinity Capture-MS Homo sapiens
2 DUSP19  
Affinity Capture-MS Homo sapiens
3 TRIM5 85363
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 TMEM52B 120939
Affinity Capture-MS Homo sapiens
5 CDC34 997
Affinity Capture-MS Homo sapiens
6 LDLRAD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 FAM189B  
Affinity Capture-MS Homo sapiens
8 SMURF2 64750
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
9 ISG15 9636
Affinity Capture-MS Homo sapiens
10 WBP2 23558
Two-hybrid Homo sapiens
11 RDH13  
Affinity Capture-MS Homo sapiens
12 APLNR  
Affinity Capture-MS Homo sapiens
13 NEDD4 4734
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
14 NHLH2  
Affinity Capture-MS Homo sapiens
15 RBPJ 3516
Affinity Capture-MS Homo sapiens
16 DUSP22  
Affinity Capture-MS Homo sapiens
17 URGCP 55665
Affinity Capture-MS Homo sapiens
18 RPL15 6138
Affinity Capture-MS Homo sapiens
19 WWP1 11059
Affinity Capture-MS Homo sapiens
20 SRPRB 58477
Affinity Capture-MS Homo sapiens
21 TMEM92  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 MAPK1 5594
Affinity Capture-MS Homo sapiens
23 MRPL30  
Affinity Capture-MS Homo sapiens
24 NFKBIA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 IKBKG 8517
Reconstituted Complex Homo sapiens
26 SURF6  
Affinity Capture-MS Homo sapiens
27 MAPK3 5595
Affinity Capture-MS Homo sapiens
28 ERLEC1 27248
Affinity Capture-MS Homo sapiens
29 SMURF1 57154
Biochemical Activity Homo sapiens
30 LRRC73  
Affinity Capture-MS Homo sapiens
31 UBC 7316
Reconstituted Complex Homo sapiens
32 ARRDC1 92714
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 MAP3K1 4214
Biochemical Activity Homo sapiens
34 TMEM51 55092
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 RPS10 6204
Affinity Capture-MS Homo sapiens
36 BIRC6 57448
Affinity Capture-MS Homo sapiens
37 ZNF114 163071
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 SPIN1  
Affinity Capture-MS Homo sapiens
39 TBP  
Affinity Capture-MS Homo sapiens
40 YAP1 10413
Affinity Capture-MS Homo sapiens
41 PTP4A3  
Affinity Capture-MS Homo sapiens
42 UBE2D2 7322
Two-hybrid Homo sapiens
43 PARK2  
Affinity Capture-MS Homo sapiens
44 ABI2 10152
Two-hybrid Homo sapiens
45 TEX264 51368
Affinity Capture-MS Homo sapiens
46 TXLNG  
Affinity Capture-MS Homo sapiens
47 STXBP4 252983
Affinity Capture-MS Homo sapiens
48 MYO6 4646
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 HECW2  
Affinity Capture-MS Homo sapiens
50 LRRK2 120892
Reconstituted Complex Homo sapiens
51 WDYHV1  
Two-hybrid Homo sapiens
52 Nedd4 25489
Biochemical Activity Rattus norvegicus
Reconstituted Complex Rattus norvegicus
53 RSL1D1 26156
Affinity Capture-MS Homo sapiens
54 SLC10A1  
Affinity Capture-MS Homo sapiens
55 OSTF1 26578
Two-hybrid Homo sapiens
56 FAM189A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 CD93  
Affinity Capture-MS Homo sapiens
58 ARRDC3 57561
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 ATP6V0A1 535
Affinity Capture-MS Homo sapiens
60 OIP5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 SMEK2  
Affinity Capture-MS Homo sapiens
62 MRPL38  
Affinity Capture-MS Homo sapiens
63 TOM1 10043
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 ITCH 83737
Affinity Capture-MS Homo sapiens
65 TMEM171  
Affinity Capture-MS Homo sapiens
66 TOM1L1 10040
Affinity Capture-MS Homo sapiens
67 PLAC9 219348
Affinity Capture-MS Homo sapiens
68 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
69 NEDD4L 23327
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
70 TOM1L2 146691
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 MYL12B 103910
Affinity Capture-MS Homo sapiens
72 MTMR6 9107
Affinity Capture-MS Homo sapiens
73 UBE2E2  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which CUEDC1 is involved
No pathways found





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