Gene description for PLAC9
Gene name placenta-specific 9
Gene symbol PLAC9
Other names/aliases -
Species Homo sapiens
 Database cross references - PLAC9
ExoCarta ExoCarta_219348
Vesiclepedia VP_219348
Entrez Gene 219348
HGNC 19255
MIM 612857
UniProt Q5JTB6  
 PLAC9 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for PLAC9
Molecular Function
    protein binding GO:0005515 IPI
Subcellular Localization
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified PLAC9 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for PLAC9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ABHD12 26090
Affinity Capture-MS Homo sapiens
2 EMC6 83460
Affinity Capture-MS Homo sapiens
3 HSPA5 3309
Affinity Capture-MS Homo sapiens
4 EMC3 55831
Affinity Capture-MS Homo sapiens
5 ZFPL1 7542
Affinity Capture-MS Homo sapiens
6 EMC7 56851
Affinity Capture-MS Homo sapiens
7 TENM3 55714
Affinity Capture-MS Homo sapiens
8 EMC4 51234
Affinity Capture-MS Homo sapiens
9 SRPR 6734
Affinity Capture-MS Homo sapiens
10 GPD2 2820
Affinity Capture-MS Homo sapiens
11 EFNB1 1947
Affinity Capture-MS Homo sapiens
12 SNAPIN 23557
Two-hybrid Homo sapiens
13 GPRASP2  
Two-hybrid Homo sapiens
14 RNF213 57674
Two-hybrid Homo sapiens
15 EMILIN2 84034
Affinity Capture-MS Homo sapiens
16 EMILIN1 11117
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
17 SSNA1 8636
Affinity Capture-MS Homo sapiens
18 RAPGEF5  
Two-hybrid Homo sapiens
19 MPZL1 9019
Affinity Capture-MS Homo sapiens
20 RAC3 5881
Affinity Capture-MS Homo sapiens
21 CCDC14  
Two-hybrid Homo sapiens
22 ATP2B4 493
Affinity Capture-MS Homo sapiens
23 CUEDC1 404093
Affinity Capture-MS Homo sapiens
24 GDPD1 284161
Affinity Capture-MS Homo sapiens
25 TMEM57  
Affinity Capture-MS Homo sapiens
26 FBXO11  
Affinity Capture-MS Homo sapiens
27 MYO18A 399687
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PLAC9 is involved
No pathways found





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