Gene description for EMILIN2
Gene name elastin microfibril interfacer 2
Gene symbol EMILIN2
Other names/aliases EMILIN-2
FOAP-10
Species Homo sapiens
 Database cross references - EMILIN2
ExoCarta ExoCarta_84034
Entrez Gene 84034
HGNC 19881
MIM 608928
UniProt Q9BXX0  
 EMILIN2 identified in exosomes derived from the following tissue/cell type
Melanoma cells 25950383    
Melanoma cells 25950383    
 Gene ontology annotations for EMILIN2
Molecular Function
    protein binding GO:0005515 IPI
    extracellular matrix constituent conferring elasticity GO:0030023 NAS
Biological Process
    cell adhesion GO:0007155 IEA
    biological_process GO:0008150 ND
Subcellular Localization
    extracellular region GO:0005576 IDA
    proteinaceous extracellular matrix GO:0005578 IEA
    extracellular matrix GO:0031012 IDA
    collagen trimer GO:0005581 IEA
 Experiment description of studies that identified EMILIN2 in exosomes
1
Experiment ID 255
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
FLOT1
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 256
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
FLOT1
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for EMILIN2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EMILIN1 11117
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which EMILIN2 is involved
PathwayEvidenceSource
Molecules associated with elastic fibres TAS Reactome





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