Experiment description of studies that identified TRHDE in sEVs

1 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

2 Experiment ID 211 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|EpCAM|TFRC Enriched markers ✔ cytochrome c|GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 212 MISEV standards ✔ CEM Biophysical techniques ✔ TSG101|Alix|EpCAM|TFRC Enriched markers ✔ Cytochrome C|GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name OVCAR-3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for TRHDE

Protein Interactor ExoCarta ID Identification method PubMed Species 1 MESDC2 23184 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 MANEA 79694 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 MUL1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 CANX 821 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 LCN6   Affinity Capture-MS Homo sapiens 6 HLA-DRA 3122 Affinity Capture-MS Homo sapiens 7 EGFR 1956 Affinity Capture-MS Homo sapiens 8 FBXO6 26270 Affinity Capture-MS Homo sapiens 9 TSPAN3 10099 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 10 FKBP14   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 TMTC3 160418 Affinity Capture-MS Homo sapiens 12 KIRREL 55243 Affinity Capture-MS Homo sapiens 13 C1QB 713 Affinity Capture-MS Homo sapiens 14 EMILIN2 84034 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 15 MAN1A2 10905 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 16 FIBIN   Affinity Capture-MS Homo sapiens 17 DNAJB9 4189 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 VAMP5 10791 Affinity Capture-MS Homo sapiens 19 AKT1 207 Affinity Capture-MS Homo sapiens 20 LEMD3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 21 ICOS   Affinity Capture-MS Homo sapiens 22 CLRN2   Affinity Capture-MS Homo sapiens View the network

Pathways in which TRHDE is involved

No pathways found