Gene description for URGCP
Gene name upregulator of cell proliferation
Gene symbol URGCP
Other names/aliases URG4
Species Homo sapiens
 Database cross references - URGCP
ExoCarta ExoCarta_55665
Entrez Gene 55665
HGNC 30890
MIM 610337
UniProt Q8TCY9  
 URGCP identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for URGCP
Molecular Function
    GTP binding GO:0005525 IEA
Biological Process
    cell cycle GO:0007049 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified URGCP in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for URGCP
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which URGCP is involved
No pathways found





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