Experiment description of studies that identified URGCP in sEVs

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

Protein-protein interactions for URGCP

Protein Interactor ExoCarta ID Identification method PubMed Species 1 DNAJC7 7266 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 ZRANB1 54764 Affinity Capture-MS Homo sapiens 3 SEC24B 10427 Affinity Capture-MS Homo sapiens 4 BAG3 9531 Affinity Capture-MS Homo sapiens 5 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 6 STUB1 10273 Affinity Capture-MS Homo sapiens 7 AAK1 22848 Affinity Capture-MS Homo sapiens 8 PLEC 5339 Affinity Capture-MS Homo sapiens 9 HSPA8 3312 Affinity Capture-MS Homo sapiens 10 BAG2 9532 Affinity Capture-MS Homo sapiens 11 DNAJA2 10294 Affinity Capture-MS Homo sapiens 12 ASPSCR1 79058 Affinity Capture-MS Homo sapiens 13 ACAD11 84129 Affinity Capture-MS Homo sapiens 14 HSPA1L 3305 Affinity Capture-MS Homo sapiens 15 UBE2D4   Affinity Capture-MS Homo sapiens 16 PPIP5K2 23262 Affinity Capture-MS Homo sapiens 17 APEX1 328 Affinity Capture-RNA Homo sapiens 18 EYA4 2070 Affinity Capture-MS Homo sapiens 19 HSPA2 3306 Affinity Capture-MS Homo sapiens 20 NTRK1 4914 Affinity Capture-MS Homo sapiens 21 CHMP5 51510 Two-hybrid Homo sapiens 22 PTGES3 10728 Affinity Capture-MS Homo sapiens 23 HECTD1 25831 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 CCDC88A 55704 Affinity Capture-MS Homo sapiens 25 CUEDC1 404093 Affinity Capture-MS Homo sapiens 26 VIM 7431 Co-fractionation Homo sapiens 27 UBE2D1 7321 Affinity Capture-MS Homo sapiens View the network

Pathways in which URGCP is involved

No pathways found