Gene description for ZBTB10
Gene name zinc finger and BTB domain containing 10
Gene symbol ZBTB10
Other names/aliases RINZF
Species Homo sapiens
 Database cross references - ZBTB10
ExoCarta ExoCarta_65986
Entrez Gene 65986
HGNC 30953
UniProt Q96DT7  
 ZBTB10 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for ZBTB10
Molecular Function
    metal ion binding GO:0046872 IEA
    DNA binding GO:0003677 IEA
    protein binding GO:0005515 IPI
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IEA
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified ZBTB10 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for ZBTB10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ZBTB10 is involved
No pathways found





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