Experiment description of studies that identified PHF23 in exosomes

1 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for PHF23

Protein Interactor ExoCarta ID Identification method PubMed Species 1 RIT1 6016 Negative Genetic Homo sapiens 2 FASN 2194 Positive Genetic Homo sapiens 3 HDAC1 3065 Affinity Capture-MS Homo sapiens 4 HMGB1 3146 Co-fractionation Homo sapiens 5 SAP130   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 KLF9 687 Proximity Label-MS Homo sapiens 7 PRSS23 11098 Two-hybrid Homo sapiens 8 TRIM55   Two-hybrid Homo sapiens 9 IGHV1-46   Affinity Capture-MS Homo sapiens 10 REN   Affinity Capture-MS Homo sapiens 11 HSP90B1 7184 Co-fractionation Homo sapiens 12 SIN3B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 13 SART1 9092 Co-fractionation Homo sapiens 14 HCCS 3052 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 15 ATXN7L1 222255 Affinity Capture-MS Homo sapiens 16 SAP30 8819 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 17 FOXK2   Affinity Capture-MS Homo sapiens 18 SF3B1 23451 Co-fractionation Homo sapiens 19 COPB2 9276 Co-fractionation Homo sapiens 20 SIN3A   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 21 BRMS1L   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 22 ARID4B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 SUDS3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 SMC2 10592 Co-fractionation Homo sapiens 25 IGLC1 3537 Affinity Capture-MS Homo sapiens 26 TRIM63   Two-hybrid Homo sapiens 27 EP300 2033 Affinity Capture-MS Homo sapiens View the network

Pathways in which PHF23 is involved

No pathways found