Gene ontology annotations for VPS51
Experiment description of studies that identified VPS51 in exosomes
1
Experiment ID
489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
4
Experiment ID
492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
5
Experiment ID
207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DKO-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
6
Experiment ID
208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
Dks-8
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
7
Experiment ID
209
MISEV standards
✘
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DLD-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
8
Experiment ID
488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Homo sapiens
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Mesenchymal stem cells
Sample name
UCMSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
9
Experiment ID
224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25944692
Organism
Homo sapiens
Experiment description
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors
"Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name
Oncotarget
Publication year
2015
Sample
Neuroblastoma cells
Sample name
SH-SY5Y
Isolation/purification methods
Differential centrifugation Ultracentrifugation OptiPrep density gradient
Flotation density
1.10 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Western blotting
10
Experiment ID
211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
11
Experiment ID
212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
12
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
13
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
14
Experiment ID
217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23844026
Organism
Homo sapiens
Experiment description
Characterization of human thymic exosomes.
Authors
"Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name
PLoS One
Publication year
2013
Sample
Thymus
Sample name
Normal-Thymus
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for VPS51
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
RAB1A
5861
Synthetic Lethality
Homo sapiens
2
METTL7A
25840
Proximity Label-MS
Homo sapiens
3
LAMP3
Proximity Label-MS
Homo sapiens
4
ATG9A
79065
Proximity Label-MS
Homo sapiens
5
GJA1
2697
Proximity Label-MS
Homo sapiens
6
CCDC132
55610
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
7
GIT2
9815
Affinity Capture-MS
Homo sapiens
8
NUP62
23636
Affinity Capture-MS
Homo sapiens
9
TRIM66
Affinity Capture-MS
Homo sapiens
10
C9orf78
51759
Affinity Capture-MS
Homo sapiens
11
GRIPAP1
56850
Affinity Capture-MS
Homo sapiens
12
LAMP2
3920
Proximity Label-MS
Homo sapiens
13
RABGAP1L
9910
Affinity Capture-MS
Homo sapiens
14
VPS54
Reconstituted Complex
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
15
ARNTL
Affinity Capture-MS
Homo sapiens
16
B3GAT1
Proximity Label-MS
Homo sapiens
17
EXOC1
55763
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
18
HLA-B
3106
Affinity Capture-MS
Homo sapiens
19
FAM174A
345757
Affinity Capture-MS
Homo sapiens
20
CDK12
51755
Co-fractionation
Homo sapiens
21
NUDT3
11165
Two-hybrid
Homo sapiens
22
PSMD9
5715
Affinity Capture-MS
Homo sapiens
23
OIP5
Affinity Capture-MS
Homo sapiens
24
HAUS6
Affinity Capture-MS
Homo sapiens
25
STX6
10228
Affinity Capture-Western
Homo sapiens
Proximity Label-MS
Homo sapiens
26
VPS53
55275
Two-hybrid
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Reconstituted Complex
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
27
RAB35
11021
Proximity Label-MS
Homo sapiens
28
EBAG9
9166
Proximity Label-MS
Homo sapiens
29
GSK3B
2932
Two-hybrid
Homo sapiens
30
LAMTOR1
55004
Proximity Label-MS
Homo sapiens
31
CCDC114
Affinity Capture-MS
Homo sapiens
32
Arrb2
Affinity Capture-MS
Mus musculus
33
BSG
682
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
34
CLOCK
Affinity Capture-MS
Homo sapiens
35
CDKN1A
Two-hybrid
Homo sapiens
36
PARK2
Affinity Capture-MS
Homo sapiens
37
EXOC4
60412
Affinity Capture-MS
Homo sapiens
38
RAB4A
5867
Proximity Label-MS
Homo sapiens
39
DTNBP1
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
40
NTRK1
4914
Affinity Capture-MS
Homo sapiens
41
GPR182
Affinity Capture-MS
Homo sapiens
42
DHH
Affinity Capture-MS
Homo sapiens
43
RPA4
Proximity Label-MS
Homo sapiens
44
SNAP29
9342
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
45
YEATS4
Affinity Capture-MS
Homo sapiens
46
NCKAP5L
Affinity Capture-MS
Homo sapiens
47
GINS2
Affinity Capture-MS
Homo sapiens
48
EFNA4
Affinity Capture-MS
Homo sapiens
49
DZIP3
Affinity Capture-MS
Homo sapiens
50
TSSC1
7260
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
51
AIFM1
9131
Affinity Capture-MS
Homo sapiens
52
RAB5A
5868
Proximity Label-MS
Homo sapiens
53
CD79B
974
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
54
TNFSF8
Affinity Capture-MS
Homo sapiens
55
LRRC25
Affinity Capture-MS
Homo sapiens
56
NPTN
27020
Affinity Capture-MS
Homo sapiens
57
MGARP
Affinity Capture-MS
Homo sapiens
58
PHLDB3
Affinity Capture-MS
Homo sapiens
59
EGFR
1956
Negative Genetic
Homo sapiens
60
TFPT
Affinity Capture-MS
Homo sapiens
61
AQP3
Affinity Capture-MS
Homo sapiens
62
PKN3
29941
Affinity Capture-MS
Homo sapiens
63
KRT27
342574
Affinity Capture-MS
Homo sapiens
64
YTHDC1
Two-hybrid
Homo sapiens
65
ARF6
382
Proximity Label-MS
Homo sapiens
66
RPA3
6119
Proximity Label-MS
Homo sapiens
67
COG8
84342
Co-fractionation
Homo sapiens
68
RAB9A
9367
Proximity Label-MS
Homo sapiens
69
PHF21A
Affinity Capture-MS
Homo sapiens
70
TUFT1
Affinity Capture-MS
Homo sapiens
71
RHOB
388
Proximity Label-MS
Homo sapiens
72
VIPR1
Affinity Capture-MS
Homo sapiens
73
DUSP16
Affinity Capture-MS
Homo sapiens
74
HMG20A
Affinity Capture-MS
Homo sapiens
75
HUWE1
10075
Affinity Capture-MS
Homo sapiens
76
DENND6A
201627
Proximity Label-MS
Homo sapiens
77
PLEKHA4
57664
Affinity Capture-MS
Homo sapiens
78
CCHCR1
Affinity Capture-MS
Homo sapiens
79
VPS52
6293
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
80
MFSD4
Affinity Capture-MS
Homo sapiens
81
OPALIN
Affinity Capture-MS
Homo sapiens
82
EDEM1
Affinity Capture-MS
Homo sapiens
83
C19orf25
Affinity Capture-MS
Homo sapiens
84
CCDC93
54520
Affinity Capture-MS
Homo sapiens
85
RCOR1
Affinity Capture-MS
Homo sapiens
86
ETS2
Affinity Capture-MS
Homo sapiens
87
GOLGA5
9950
Affinity Capture-MS
Homo sapiens
88
C16orf72
29035
Affinity Capture-MS
Homo sapiens
89
RAB11A
8766
Proximity Label-MS
Homo sapiens
90
KXD1
79036
Affinity Capture-MS
Homo sapiens
91
ZUFSP
221302
Affinity Capture-MS
Homo sapiens
92
KRAS
3845
Proximity Label-MS
Homo sapiens
93
AR
367
Affinity Capture-MS
Homo sapiens
94
CCDC96
Affinity Capture-MS
Homo sapiens
95
PTRF
284119
Affinity Capture-MS
Homo sapiens
96
LURAP1
Affinity Capture-MS
Homo sapiens
97
RPRD1A
Affinity Capture-MS
Homo sapiens
98
C17orf59
54785
Proximity Label-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
99
CDC5L
988
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which VPS51 is involved