Experiment description of studies that identified ZBTB7A in exosomes

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 236 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

3 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for ZBTB7A

Protein Interactor ExoCarta ID Identification method PubMed Species 1 UTP20 27340 Co-fractionation Homo sapiens 2 RELA 5970 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 3 HNRNPH1 3187 Affinity Capture-RNA Homo sapiens 4 HDAC2 3066 Affinity Capture-Western Homo sapiens 5 EEF1A1 1915 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 6 SIN3A   Affinity Capture-Western Homo sapiens 7 TP53 7157 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 8 Cebpb   Affinity Capture-Western Rattus norvegicus 9 HOMEZ   Two-hybrid Homo sapiens 10 RB1 5925 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 11 NCOR2   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 12 E2F1 1869 Affinity Capture-Western Homo sapiens 13 SREBF1 6720 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 14 TFAP4 7023 Affinity Capture-MS Homo sapiens 15 HIST1H4A 8359 Affinity Capture-MS Homo sapiens 16 SMAD4   Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 17 CUL3 8452 Affinity Capture-MS Homo sapiens 18 HDAC1 3065 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 19 HSP90AA1 3320 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 20 TAF1   Affinity Capture-MS Homo sapiens 21 SIRT1   Affinity Capture-Western Homo sapiens 22 MKI67   Affinity Capture-MS Homo sapiens 23 PRKDC 5591 Affinity Capture-MS Homo sapiens 24 ZBTB48   Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 25 UBE2I 7329 Biochemical Activity Homo sapiens 26 HDAC3 8841 Affinity Capture-Western Homo sapiens 27 NCOR1   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 28 SP1   Co-localization Homo sapiens Affinity Capture-Western Homo sapiens 29 ZMYND8 23613 Two-hybrid Homo sapiens 30 ETS1   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 31 XRCC6 2547 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 32 Sp1 20683 Reconstituted Complex Mus musculus 33 BCL6   Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 34 SOX9   Affinity Capture-Western Homo sapiens 35 AR 367 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 36 NFKBIB   Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 37 ZBTB7C   Affinity Capture-MS Homo sapiens 38 NFKBIA   Affinity Capture-Western Homo sapiens 39 ZBTB7A 51341 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Co-crystal Structure Homo sapiens FRET Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Co-crystal Structure Homo sapiens FRET Homo sapiens 40 XRCC5 7520 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 41 BCOR   Affinity Capture-Western Homo sapiens 42 KHDRBS1 10657 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 43 FEV   Proximity Label-MS Homo sapiens View the network

Pathways in which ZBTB7A is involved

No pathways found