Gene description for Sp1
Gene name	trans-acting transcription factor 1
Gene symbol	Sp1
Other names/aliases	1110003E12Rik AA450830 AI845540 Sp1-1
Species	Mus musculus
Database cross references - Sp1
ExoCarta	ExoCarta_20683
Vesiclepedia	VP_20683
Entrez Gene	20683
UniProt	O89090
Sp1 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Sp1

Molecular Function     transcription cis-regulatory region binding GO:0000976 ISO     RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000977 ISO     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 ISO     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 ISS     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IDA     cis-regulatory region sequence-specific DNA binding GO:0000987 IDA     transcription coregulator binding GO:0001221 ISO     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IDA     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 ISO     DNA binding GO:0003677 IDA     DNA binding GO:0003677 ISO     DNA binding GO:0003677 ISS     double-stranded DNA binding GO:0003690 IDA     double-stranded DNA binding GO:0003690 ISO     DNA-binding transcription factor activity GO:0003700 IDA     DNA-binding transcription factor activity GO:0003700 IMP     DNA-binding transcription factor activity GO:0003700 ISO     protein binding GO:0005515 IPI     protein binding GO:0005515 IPI     histone acetyltransferase binding GO:0035035 ISO     identical protein binding GO:0042802 ISO     protein homodimerization activity GO:0042803 ISO     histone deacetylase binding GO:0042826 ISO     bHLH transcription factor binding GO:0043425 IPI     sequence-specific DNA binding GO:0043565 IDA     sequence-specific DNA binding GO:0043565 ISO     metal ion binding GO:0046872 IEA     molecular adaptor activity GO:0060090 ISO     RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 IPI     sequence-specific double-stranded DNA binding GO:1990837 ISO Biological Process     ossification GO:0001503 IGI     in utero embryonic development GO:0001701 IGI     trophectodermal cell differentiation GO:0001829 IGI     liver development GO:0001889 IGI     embryonic placenta development GO:0001892 IGI     myeloid progenitor cell differentiation GO:0002318 IGI     regulation of DNA-templated transcription GO:0006355 IMP     regulation of DNA-templated transcription GO:0006355 IMP     regulation of DNA-templated transcription GO:0006355 ISO     regulation of transcription by RNA polymerase II GO:0006357 IBA     regulation of transcription by RNA polymerase II GO:0006357 ISO     gene expression GO:0010467 ISS     positive regulation of gene expression GO:0010628 ISO     megakaryocyte differentiation GO:0030219 IGI     lung development GO:0030324 IGI     cellular response to insulin stimulus GO:0032869 ISO     response to hydroperoxide GO:0033194 IDA     mRNA transcription by RNA polymerase II GO:0042789 IDA     enucleate erythrocyte differentiation GO:0043353 IGI     positive regulation of blood vessel endothelial cell migration GO:0043536 ISO     positive regulation by host of viral transcription GO:0043923 ISO     positive regulation of angiogenesis GO:0045766 ISO     positive regulation of DNA-templated transcription GO:0045893 IDA     positive regulation of DNA-templated transcription GO:0045893 IDA     positive regulation of DNA-templated transcription GO:0045893 ISO     positive regulation of DNA-templated transcription GO:0045893 ISO     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IGI     positive regulation of transcription by RNA polymerase II GO:0045944 IMP     positive regulation of transcription by RNA polymerase II GO:0045944 ISO     rhythmic process GO:0048511 IEA     embryonic camera-type eye morphogenesis GO:0048596 IGI     embryonic skeletal system development GO:0048706 IGI     embryonic process involved in female pregnancy GO:0060136 IGI     definitive hemopoiesis GO:0060216 IGI     positive regulation of amyloid-beta formation GO:1902004 ISO     positive regulation of hydrogen sulfide biosynthetic process GO:1904828 ISO     positive regulation of vascular endothelial cell proliferation GO:1905564 ISO Subcellular Localization     chromatin GO:0000785 IDA     chromatin GO:0000785 ISO     euchromatin GO:0000791 ISO     nucleus GO:0005634 IDA     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 IEA     transcription repressor complex GO:0017053 ISO     protein-containing complex GO:0032991 ISS     protein-DNA complex GO:0032993 ISO