Gene description for Hdac1
Gene name	histone deacetylase 1
Gene symbol	Hdac1
Other names/aliases	HD1 Hdac1-ps MommeD5 RPD3
Species	Mus musculus
Database cross references - Hdac1
ExoCarta	ExoCarta_433759
Entrez Gene	433759
UniProt	O09106
Hdac1 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Hdac1

Molecular Function     RNA polymerase II repressing transcription factor binding GO:0001103 ISO     RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980 ISO     transcription regulatory region sequence-specific DNA binding GO:0000976 IDA     histone deacetylase activity GO:0004407 ISO     enzyme binding GO:0019899 ISO     protein N-terminus binding GO:0047485 ISO     protein binding GO:0005515 IPI     Krueppel-associated box domain binding GO:0035851 IPI     deacetylase activity GO:0019213 IDA     DNA binding GO:0003677 IDA     transcription corepressor activity GO:0003714 IDA     activating transcription factor binding GO:0033613 ISO     histone deacetylase binding GO:0042826 ISO     transcription factor binding GO:0008134 TAS     sequence-specific DNA binding transcription factor activity GO:0003700 IDA     histone deacetylase activity (H3-K14 specific) GO:0031078 IEA     NAD-dependent histone deacetylase activity (H3-K18 specific) GO:0097372 IEA     NAD-dependent histone deacetylase activity (H4-K16 specific) GO:0046970 IEA     RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978 ISO     core promoter binding GO:0001047 ISO     hydrolase activity GO:0016787 IEA     NF-kappaB binding GO:0051059 ISO     chromatin binding GO:0003682 ISO     RNA polymerase II transcription corepressor activity GO:0001106 ISO     protein deacetylase activity GO:0033558 ISO     histone deacetylase activity (H3-K9 specific) GO:0032129 IEA     NAD-dependent histone deacetylase activity (H3-K14 specific) GO:0032041 IEA     transcription regulatory region DNA binding GO:0044212 ISO     protein complex binding GO:0032403 ISO     histone deacetylase activity (H4-K16 specific) GO:0034739 IEA     nucleosomal DNA binding GO:0031492 ISO     repressing transcription factor binding GO:0070491 ISO     NAD-dependent histone deacetylase activity (H3-K9 specific) GO:0046969 IEA Biological Process     negative regulation of insulin secretion GO:0046676 ISO     hair follicle placode formation GO:0060789 IGI     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISO     transcription from RNA polymerase II promoter GO:0006366 ISO     embryonic digit morphogenesis GO:0042733 IGI     protein deacetylation GO:0006476 ISO     negative regulation of I-kappaB kinase/NF-kappaB signaling GO:0043124 IGI     negative regulation of canonical Wnt signaling pathway GO:0090090 IGI     negative regulation of androgen receptor signaling pathway GO:0060766 ISO     positive regulation of chemokine (C-X-C motif) ligand 2 production GO:2000343 ISO     regulation of transcription, DNA-templated GO:0006355 IEA     histone H4 deacetylation GO:0070933 ISO     positive regulation of cell proliferation GO:0008284 ISO     positive regulation of receptor biosynthetic process GO:0010870 ISO     negative regulation by host of viral transcription GO:0043922 ISO     eyelid development in camera-type eye GO:0061029 IGI     transcription, DNA-templated GO:0006351 IEA     response to amphetamine GO:0001975 ISO     negative regulation of transcription from RNA polymerase II promoter GO:0000122 ISO     positive regulation of tumor necrosis factor production GO:0032760 ISO     positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 ISO     neuron differentiation GO:0030182 IGI     negative regulation of neuron apoptotic process GO:0043524 ISO     chromatin modification GO:0016568 TAS     negative regulation of apoptotic process GO:0043066 IGI     negative regulation of cell proliferation GO:0008285 ISO     circadian rhythm GO:0007623 IDA     cellular response to oxidative stress GO:0034599 ISO     positive regulation of oligodendrocyte differentiation GO:0048714 ISO     positive regulation of interleukin-1 production GO:0032732 ISO     epidermal cell differentiation GO:0009913 IGI     fungiform papilla formation GO:0061198 IGI     circadian regulation of gene expression GO:0032922 IDA     negative regulation of intrinsic apoptotic signaling pathway GO:2001243 IGI     positive regulation of type B pancreatic cell apoptotic process GO:2000676 ISO     positive regulation of transcription, DNA-templated GO:0045893 ISO     negative regulation of gene expression GO:0010629 ISO     negative regulation of transcription, DNA-templated GO:0045892 ISO     histone H3 deacetylation GO:0070932 ISO     negative regulation of peptidyl-lysine acetylation GO:2000757 ISO     endoderm development GO:0007492 IMP     histone deacetylation GO:0016575 ISO     hippocampus development GO:0021766 IGI     odontogenesis of dentin-containing tooth GO:0042475 IGI     rhythmic process GO:0048511 IEA     ATP-dependent chromatin remodeling GO:0043044 ISO Subcellular Localization     nuclear chromatin GO:0000790 ISO     NuRD complex GO:0016581 ISO     cytosol GO:0005829 ISO     neuron projection GO:0043005 ISO     transcription factor complex GO:0005667 IPI     perinuclear region of cytoplasm GO:0048471 ISO     nucleus GO:0005634 ISO     cytoplasm GO:0005737 TAS     protein complex GO:0043234 ISO     nucleoplasm GO:0005654 ISO     transcriptional repressor complex GO:0017053 IPI     Sin3 complex GO:0016580 ISO     chromatin GO:0000785 ISO     histone deacetylase complex GO:0000118 TAS     neuronal cell body GO:0043025 IDA     heterochromatin GO:0000792 IDA