Gene description for Rbbp7
Gene name retinoblastoma binding protein 7
Gene symbol Rbbp7
Other names/aliases AA409861
AI173248
AU019541
BB114024
mRbAp46
Species Mus musculus
 Database cross references - Rbbp7
ExoCarta ExoCarta_245688
Vesiclepedia VP_245688
Entrez Gene 245688
UniProt Q60973  
 Rbbp7 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Rbbp7
Molecular Function
    RNA binding GO:0003723 IPI
    protein binding GO:0005515 IPI
Biological Process
    transcription, DNA-templated GO:0006351 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
    chromatin modification GO:0016568 IEA
    cellular heat acclimation GO:0070370 ISS
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IDA
    DNA replication GO:0006260 IEA
    negative regulation of cell growth GO:0030308 ISO
    chromatin remodeling GO:0006338 TAS
    negative regulation of transcription, DNA-templated GO:0045892 IDA
Subcellular Localization
    ESC/E(Z) complex GO:0035098 ISO
    NuRD complex GO:0016581 ISO
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Rbbp7 in exosomes
1
Experiment ID 907
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Rbbp7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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