Gene description for Rbbp4
Gene name retinoblastoma binding protein 4
Gene symbol Rbbp4
Other names/aliases RBAP48
Species Mus musculus
 Database cross references - Rbbp4
ExoCarta ExoCarta_19646
Entrez Gene 19646
UniProt Q60972  
 Rbbp4 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Rbbp4
Molecular Function
    DNA-dependent ATPase activity GO:0008094 ISO
    RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978 ISO
    nucleosomal DNA binding GO:0031492 ISO
    protein binding GO:0005515 IPI
    histone deacetylase binding GO:0042826 ISO
    RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980 ISO
Biological Process
    ATP-dependent chromatin remodeling GO:0043044 ISO
    regulation of transcription, DNA-templated GO:0006355 IEA
    DNA replication GO:0006260 IEA
    transcription, DNA-templated GO:0006351 IEA
    chromatin assembly GO:0031497 ISO
    chromatin remodeling GO:0006338 TAS
    DNA replication-independent nucleosome assembly GO:0006336 ISO
    chromatin modification GO:0016568 IEA
    cell cycle GO:0007049 IEA
    DNA replication-dependent nucleosome assembly GO:0006335 ISO
Subcellular Localization
    NuRD complex GO:0016581 ISO
    nucleus GO:0005634 ISO
    protein complex GO:0043234 ISO
    CAF-1 complex GO:0033186 ISO
    nuclear chromatin GO:0000790 ISO
    nucleoplasm GO:0005654 ISO
    NURF complex GO:0016589 ISO
    ESC/E(Z) complex GO:0035098 ISO
 Experiment description of studies that identified Rbbp4 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Rbbp4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here