Gene description for Tle1
Gene name	transducin-like enhancer of split 1, homolog of Drosophila E(spl)
Gene symbol	Tle1
Other names/aliases	C230057C06Rik Estm14 Grg-1 Grg1 Tle4l
Species	Mus musculus
Database cross references - Tle1
ExoCarta	ExoCarta_21885
Vesiclepedia	VP_21885
Entrez Gene	21885
UniProt	Q62440
Tle1 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Tle1

Molecular Function     chromatin binding GO:0003682 IDA     transcription corepressor activity GO:0003714 IBA     transcription corepressor activity GO:0003714 IDA     transcription corepressor activity GO:0003714 ISO     protein binding GO:0005515 IPI     identical protein binding GO:0042802 ISO     DNA-binding transcription factor binding GO:0140297 ISO Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IDA     regulation of DNA-templated transcription GO:0006355 IDA     regulation of transcription by RNA polymerase II GO:0006357 IGI     positive regulation of gene expression GO:0010628 ISO     Wnt signaling pathway GO:0016055 IEA     negative regulation of Wnt signaling pathway GO:0030178 ISO     negative regulation of canonical NF-kappaB signal transduction GO:0043124 ISO     negative regulation of canonical NF-kappaB signal transduction GO:0043124 ISS     negative regulation of DNA-templated transcription GO:0045892 ISO     negative regulation of canonical Wnt signaling pathway GO:0090090 IBA     negative regulation of anoikis GO:2000811 ISO Subcellular Localization     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 ISO     transcription regulator complex GO:0005667 IBA     transcription regulator complex GO:0005667 IDA     cytoplasm GO:0005737 IEA     cytosol GO:0005829 ISO     beta-catenin-TCF complex GO:1990907 ISO