Gene description for Ss18
Gene name synovial sarcoma translocation, Chromosome 18
Gene symbol Ss18
Other names/aliases D130059H17
Ssxt
Syt
Species Mus musculus
 Database cross references - Ss18
ExoCarta ExoCarta_268996
Entrez Gene 268996
UniProt Q62280  
 Ss18 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ss18
Molecular Function
    ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 ISO
Biological Process
    cytoskeleton organization GO:0007010 IDA
    microtubule cytoskeleton organization GO:0000226 IDA
    neuronal stem cell maintenance GO:0097150 IMP
    regulation of transcription, DNA-templated GO:0006355 IEA
    transcription, DNA-templated GO:0006351 IEA
    cell morphogenesis GO:0000902 IGI
    intracellular signal transduction GO:0035556 IDA
    ephrin receptor signaling pathway GO:0048013 IDA
    response to drug GO:0042493 IDA
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISO
Subcellular Localization
    npBAF complex GO:0071564 IDA
    nucleus GO:0005634 IEA
    cytoplasmic microtubule GO:0005881 IDA
 Experiment description of studies that identified Ss18 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ss18
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ss18 is involved
No pathways found





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