Gene description for Ss18
Gene name synovial sarcoma translocation, Chromosome 18
Gene symbol Ss18
Other names/aliases D130059H17
Ssxt
Syt
Species Mus musculus
 Database cross references - Ss18
ExoCarta ExoCarta_268996
Vesiclepedia VP_268996
Entrez Gene 268996
UniProt Q62280  
 Ss18 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ss18
Molecular Function
    transcription coactivator activity GO:0003713 IBA
    nuclear receptor coactivator activity GO:0030374 IEA
    nuclear receptor coactivator activity GO:0030374 ISO
Biological Process
    microtubule cytoskeleton organization GO:0000226 IDA
    cell morphogenesis GO:0000902 IDA
    cell morphogenesis GO:0000902 IGI
    chromatin remodeling GO:0006338 NAS
    regulation of transcription by RNA polymerase II GO:0006357 NAS
    cytoskeleton organization GO:0007010 IDA
    positive regulation of cell population proliferation GO:0008284 NAS
    response to xenobiotic stimulus GO:0009410 IDA
    intracellular signal transduction GO:0035556 IDA
    negative regulation of cell differentiation GO:0045596 NAS
    positive regulation of transcription by RNA polymerase II GO:0045944 IBA
    positive regulation of transcription by RNA polymerase II GO:0045944 IEA
    positive regulation of transcription by RNA polymerase II GO:0045944 ISO
    ephrin receptor signaling pathway GO:0048013 IDA
    neuronal stem cell population maintenance GO:0097150 IMP
    positive regulation of stem cell population maintenance GO:1902459 NAS
Subcellular Localization
    chromatin GO:0000785 NAS
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 TAS
    microtubule cytoskeleton GO:0015630 IDA
    SWI/SNF complex GO:0016514 IDA
    SWI/SNF complex GO:0016514 ISO
    npBAF complex GO:0071564 IDA
    GBAF complex GO:0140288 NAS
 Experiment description of studies that identified Ss18 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ss18
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Atf2  
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
2 Tle1 21885
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
3 Hdac1 433759
Affinity Capture-Western Mus musculus
4 Ezh2  
Affinity Capture-Western Mus musculus
View the network image/svg+xml
 Pathways in which Ss18 is involved
No pathways found





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